Publications

Huang BZ, Binder AM, Sugar CA, Chao CR, Setiawan VW, Zhang ZF. Methylation of immuneregulatory cytokine genes and pancreatic cancer outcomes. Epigenomics. 2020 August;12(15):1273-1285. PubMed PMID: 32867538; PubMed Central PMCID: PMC7546161; DOI: 10.2217/epi-2019-0335.

Michels KB, Keller K, Pereira A, Kim CE, Santos JL, Shepherd J, Corvalan C, Binder AM. Association between indicators of systemic inflammation biomarkers during puberty with breast density and onset of menarche. Breast cancer research : BCR. 2020 October 1;22(1):104. PubMed PMID: 33004039; PubMed Central PMCID: PMC7531086; DOI: 10.1186/s13058-020-01338-y.

Yan Q, Paul KC, Lu AT, Kusters C, Binder AM, Horvath S, Ritz B. Epigenetic mutation load is weakly correlated with epigenetic age acceleration. Aging. 2020 September 29;12(18):17863-17894. PubMed PMID: 32991324; PubMed Central PMCID: PMC7585066; DOI: 10.18632/aging.103950.

Clausing ES, Binder AM, Non AL. Epigenetic age associates with psychosocial stress and resilience in children of Latinx immigrants. Epigenomics. 2021 Nov;13(21):1677-1699. doi: 10.2217/epi-2019-0343. Epub 2021 Mar 22. PMID: 33749330.

McCartney DL, Min JL, Richmond RC, Lu AT, Sobczyk MK, Davies G, Broer L, Guo X, Jeong A, Jung J, Kasela S, Katrinli S, Kuo PL, Matias-Garcia PR, Mishra PP, Nygaard M, Palviainen T, Patki A, Raffield LM, Ratliff SM, Richardson TG, Robinson O, Soerensen M, Sun D, Tsai PC, van der Zee MD, Walker RM, Wang X, Wang Y, Xia R, Xu Z, Yao J, Zhao W, Correa A, Boerwinkle E, Dugué PA, Durda P, Elliott HR, Gieger C; Genetics of DNA Methylation Consortium, de Geus EJC, Harris SE, Hemani G, Imboden M, Kähönen M, Kardia SLR, Kresovich JK, Li S, Lunetta KL, Mangino M, Mason D, McIntosh AM, Mengel-From J, Moore AZ, Murabito JM; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Ollikainen M, Pankow JS, Pedersen NL, Peters A, Polidoro S, Porteous DJ, Raitakari O, Rich SS, Sandler DP, Sillanpää E, Smith AK, Southey MC, Strauch K, Tiwari H, Tanaka T, Tillin T, Uitterlinden AG, Van Den Berg DJ, van Dongen J, Wilson JG, Wright J, Yet I, Arnett D, Bandinelli S, Bell JT, Binder AM, Boomsma DI, Chen W, Christensen K, Conneely KN, Elliott P, Ferrucci L, Fornage M, Hägg S, Hayward C, Irvin M, Kaprio J, Lawlor DA, Lehtimäki T, Lohoff FW, Milani L, Milne RL, Probst-Hensch N, Reiner AP, Ritz B, Rotter JI, Smith JA, Taylor JA, van Meurs JBJ, Vineis P, Waldenberger M, Deary IJ, Relton CL, Horvath S, Marioni RE. Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging. Genome Biol. 2021 Jun 29;22(1):194. doi: 10.1186/s13059-021-02398-9. PMID: 34187551; PMCID: PMC8243879.

Paul KC, Binder AM, Horvath S, Kusters C, Yan Q, Rosario ID, Yu Y, Bronstein J, Ritz B. Accelerated hematopoietic mitotic aging measured by DNA methylation, blood cell lineage, and Parkinson’s disease. BMC Genomics. 2021 Sep 26;22(1):696. doi: 10.1186/s12864-021-08009-y. PMID: 34565328; PMCID: PMC8474781.

Welch BM, Keil AP, Buckley JP, Calafat AM, Christenbury KE, Engel SM, O’Brien KM, Rosen EM, James-Todd T, Zota AR, Ferguson KK, Alshawabkeh AN, Cordero JF, Meeker JD, Barrett ES, Bush NR, Nguyen RHN, Sathyanarayana S, Swan SH, Cantonwine DE, McElrath TF, Aalborg J, Dabelea D, Starling AP, Hauser R, Messerlian C, Zhang Y, Bradman A, Eskenazi B, Harley KG, Holland N, Bloom MS, Newman RB, Wenzel AG, Braun JM, Lanphear BP, Yolton K, Factor-Litvak P, Herbstman JB, Rauh VA, Drobnis EZ, Sparks AE, Redmon JB, Wang C, Binder AM, Michels KB, Baird DD, Jukic AMZ, Weinberg CR, Wilcox AJ, Rich DQ, Weinberger B, Padmanabhan V, Watkins DJ, Hertz-Picciotto I, Schmidt RJ. Associations Between Prenatal Urinary Biomarkers of Phthalate Exposure and Preterm Birth: A Pooled Study of 16 US Cohorts. JAMA Pediatr. 2022 Jul 11;. doi: 10.1001/jamapediatrics.2022.2252. [Epub ahead of print] PubMed PMID: 35816333.

Jain P, Binder AM, Chen B, Parada H Jr, Gallo LC, Alcaraz J, Horvath S, Bhatti P, Whitsel EA, Jordahl K, Baccarelli AA, Hou L, Stewart JD, Li Y, Justice JN, LaCroix AZ. Analysis of Epigenetic Age Acceleration and Healthy Longevity Among Older US Women. JAMA Netw Open. 2022 Jul 1;5(7):e2223285. doi: 10.1001/jamanetworkopen.2022.23285. PMID: 35895062; PMCID: PMC9331104.

Jain P, Binder A, Chen B, Parada H, Gallo LC, Alcaraz J, Horvath S, Bhatti P, Whitsel EA, Jordahl K, Baccarelli AA, Hou L, Stewart JD, Li Y, LaMonte MJ, Manson JE, LaCroix AZ. The association of epigenetic age acceleration and multimorbidity at age 90 in the Women’s Health Initiative. J Gerontol A Biol Sci Med Sci. 2022 Sep 15:glac190. doi: 10.1093/gerona/glac190. Epub ahead of print. PMID: 36107798.

Fernandez-Jimenez N, Fore R, Cilleros-Portet A, Lepeule J, Perron P, Kvist T, Tian FY, Lesseur C, Binder AM, Lozano M, Martorell-Marugán J, Loke YJ, Bakulski KM, Zhu Y, Forhan A, Sammallahti S, Everson TM, Chen J, Michels KB, Belmonte T, Carmona-Sáez P, Halliday J, Daniele Fallin M, LaSalle JM, Tost J, Czamara D, Fernández MF, Gómez-Martín A, Craig JM, Gonzalez-Alzaga B, Schmidt RJ, Dou JF, Muggli E, Lacasaña M, Vrijheid M, Marsit CJ, Karagas MR, Räikkönen K, Bouchard L, Heude B, Santa-Marina L, Bustamante M, Hivert MF, Bilbao JR. A meta-analysis of pre-pregnancy maternal body mass index and placental DNA methylation identifies 27 CpG sites with implications for mother-child health. Commun Biol. 2022 Nov 30;5(1):1313. doi: 10.1038/s42003-022-04267-y. PMID: 36446949; PMCID: PMC9709064.

Lu AT, Binder AM, Zhang J, Yan Q, Reiner AP, Cox SR, Corley J, Harris SE, Kuo PL, Moore AZ, Bandinelli S, Stewart JD, Wang C, Hamlat EJ, Epel ES, Schwartz JD, Whitsel EA, Correa A, Ferrucci L, Marioni RE, Horvath S. DNA methylation GrimAge version 2. Aging (Albany NY). 2022 Dec 14;14(23):9484-9549. doi: 10.18632/aging.204434. Epub 2022 Dec 14. PMID: 36516495; PMCID: PMC9792204.

Yoon LS, Binder AM, Pereira A, Calafat AM, Shepherd J, Corvalán C, Michels KB. Variability in urinary phthalates, phenols, and parabens across childhood and relation to adolescent breast composition in Chilean girls. Environ Int. 2022 Dec;170:107586. doi: 10.1016/j.envint.2022.107586. Epub 2022 Oct 19. PMID: 36302292.

McGreevy KM, Radak Z, Torma F, Jokai M, Lu AT, Belsky DW, Binder A, Marioni RE, Ferrucci L, Pośpiech E, Branicki W, Ossowski A, Sitek A, Spólnicka M, Raffield LM, Reiner AP, Cox S, Kobor M, Corcoran DL, Horvath S. DNAmFitAge: biological age indicator incorporating physical fitness. Aging (Albany NY). 2023 Feb 22;15. doi: 10.18632/aging.204538. Epub ahead of print. PMID: 36812475.

Cespedes Feliciano EM, Vasan S, Luo J, Binder AM, Chlebowski RT, Quesenberry C, Banack HR, Caan BJ, Paskett ED, Williams GR, Barac A, LaCroix AZ, Peters U, Reding KW, Pan K, Shadyab AH, Qi L, Anderson GL. Long-term Trajectories of Physical Function Decline in Women With and Without Cancer. JAMA Oncol. 2023 Mar 1;9(3):395-403. doi: 10.1001/jamaoncol.2022.6881. PMID: 36656572; PMCID: PMC9857739.

Kim DH, Binder AM, Zhou H, Jung SY. DNA methylation patterns associated with breast cancer prognosis that are specific to tumor subtype and menopausal status. Front Genet. 2023 Mar 2;14:1133443. doi: 10.3389/fgene.2023.1133443. PMID: 36936429; PMCID: PMC10018014.

Kusters CD, Paul KC, Lu AT, Ferrucci L, Ritz BR, Binder AM, Horvath S. Higher testosterone and testosterone/estradiol ratio in men are associated with better epigenetic estimators of mortality risk. medRxiv [Preprint]. 2023 Jul 30:2023.02.16.23285997. doi: 10.1101/2023.02.16.23285997. Update in: Geroscience. 2023 Jun 27;: PMID: 36865294; PMCID: PMC9980235.

Kim CE, Binder AM, Corvalan C, Pereira A, Shepherd J, Calafat AM, Botelho JC, Hampton JM, Trentham-Dietz A, Michels KB. Time-specific impact of mono-benzyl phthalate (MBzP) and perfluorooctanoic acid (PFOA) on breast density of a Chilean adolescent Cohort. Environ Int. 2023 Nov;181:108241. doi: 10.1016/j.envint.2023.108241. Epub 2023 Sep 28. PMID: 37857187.

Cheng E, Caan BJ, Cawthon PM, Evans WJ, Hellerstein MK, Shankaran M, Nyangau E, Campbell KL, Lee C, Binder AM, Meyerhardt JA, Schmitz KH, Cespedes Feliciano EM. Body Composition, Relative Dose Intensity, and Adverse Events among Patients with Colon Cancer. Cancer Epidemiol Biomarkers Prev. 2023 Oct 2;32(10):1373-1381. doi: 10.1158/1055-9965.EPI-23-0227. PMID: 37450841; PMCID: PMC10592319.

Pereira A, Ferrer P, Binder A, Rojas J, Michels KB, Corvalán C, Mericq V. Association Between Markers of Adiposity During Childhood and Puberty Onset in Latino Girls. J Clin Endocrinol Metab. 2023 Oct 18;108(11):e1272-e1281. doi: 10.1210/clinem/dgad294. PMID: 37226986.

Cheng E, Caan BJ, Cawthon PM, Evans WJ, Hellerstein MK, Shankaran M, Campbell KL, Binder AM, Sternfeld B, Meyerhardt JA, Schmitz KH, Cespedes Feliciano EM. D3-creatine dilution, computed tomography and dual-energy X-ray absorptiometry for assessing myopenia and physical function in colon cancer: A cross-sectional study. J Cachexia Sarcopenia Muscle. 2023 Dec;14(6):2768-2778. doi: 10.1002/jcsm.13353. Epub 2023 Oct 30. PMID: 37899757; PMCID: PMC10751410.

Kusters CDJ, Paul KC, Lu AT, Ferruci L, Ritz BR, Binder AM, Horvath S. Higher testosterone and testosterone/estradiol ratio in men are associated with decreased Pheno-/GrimAge and DNA-methylation based PAI1. Geroscience. 2024 Feb;46(1):1053-1069. doi: 10.1007/s11357-023-00832-3. Epub 2023 Jun 27. Erratum in: Geroscience. 2023 Nov 3;: PMID: 37369886; PMCID: PMC10828310.

Ponce D, Rodríguez F, Miranda JP, Binder AM, Santos JL, Michels KB, Cutler GB Jr, Pereira A, Iñiguez G, Mericq V. Differential methylation pattern in pubertal girls associated with biochemical premature adrenarche. Epigenetics. 2023 Dec;18(1):2200366. doi: 10.1080/15592294.2023.2200366. PMID: 37053179; PMCID: PMC10114989.

Michels KB, Binder AM. Impact of folic acid supplementation on the epigenetic profile in healthy unfortified individuals - a randomized intervention trial. Epigenetics. 2024 Dec;19(1):2293410. doi: 10.1080/15592294.2023.2293410. Epub 2023 Dec 14. PMID: 38096372; PMCID: PMC10730197.

Welch BM, Keil AP, Buckley JP, Engel SM, James-Todd T, Zota AR, Alshawabkeh AN, Barrett ES, Bloom MS, Bush NR, Cordero JF, Dabelea D, Eskenazi B, Lanphear BP, Padmanabhan V, Sathyanarayana S, Swan SH, Aalborg J, Baird DD, Binder AM, Bradman A, Braun JM, Calafat AM, Cantonwine DE, Christenbury KE, Factor-Litvak P, Harley KG, Hauser R, Herbstman JB, Hertz-Picciotto I, Holland N, Jukic AMZ, McElrath TF, Meeker JD, Messerlian C, Michels KB, Newman RB, Nguyen RHN, O'Brien KM, Rauh VA, Redmon B, Rich DQ, Rosen EM, Schmidt RJ, Sparks AE, Starling AP, Wang C, Watkins DJ, Weinberg CR, Weinberger B, Wenzel AG, Wilcox AJ, Yolton K, Zhang Y, Ferguson KK. Racial and Ethnic Disparities in Phthalate Exposure and Preterm Birth: A Pooled Study of Sixteen U.S. Cohorts. Environ Health Perspect. 2023 Dec;131(12):127015. doi: 10.1289/EHP12831. Epub 2023 Dec 20. PMID: 38117586; PMCID: PMC10732302.

Caan BJ, Brown JC, Lee C, Binder AM, Weltzien E, Ross MC, Quesenberry CP, Campbell KL, Cespedes Feliciano EM, Castillo A, Quinney S, Yang S, Meyerhardt JA, Schmitz KH. Effect of home-based resistance training on chemotherapy relative dose intensity and tolerability in colon cancer: The FORCE randomized control trial. Cancer. 2024 Jan 24. doi: 10.1002/cncr.35204. Epub ahead of print. PMID: 38265970.

Kusters CDJ, Paul KC, Lu AT, Ferrucci L, Ritz BR, Binder AM, Horvath S. Correction to: Higher testosterone and testosterone/estradiol ratio in men are associated with decreased Pheno‑/GrimAge and DNA‑methylation based PAI1. Geroscience. 2024 Apr;46(2):2791-2792. doi: 10.1007/s11357-023-00995-z. Erratum for: Geroscience. 2024 Feb;46(1):1053-1069. PMID: 37921956; PMCID: PMC10828359.

Huang BZ, Binder AM, Quon B, Patel YM, Lum-Jones A, Tiirikainen M, Murphy SE, Loo L, Maunakea AK, Haiman CA, Wilkens LR, Koh WP, Cai Q, Aldrich MC, Siegmund KD, Hecht SS, Yuan JM, Blot WJ, Stram DO, Le Marchand L, Park SL. Epigenome-wide association study of total nicotine equivalents in multiethnic current smokers from three prospective cohorts. Am J Hum Genet. 2024 Feb 16:S0002-9297(24)00031-4. doi: 10.1016/j.ajhg.2024.01.012. Epub ahead of print. PMID: 38367619.

Bareja A, Lee DE, Ho T, Waitt G, McKay LH, Hannou SA, Orenduff MC, McGreevy KM, Binder A, Ryan CP, Soderblom EJ, Belsky DW, Ferrucci L, Das JK, Banskota N, Kraus VB, Huebner JL, Kraus WE, Huffman KM, Baht GS, Horvath S, Parmer RJ, Miles LA, White JP. Liver-derived plasminogen mediates muscle stem cell expansion during caloric restriction through the plasminogen receptor Plg-RKT. Cell Rep. 2024 Mar 4;43(3):113881. doi: 10.1016/j.celrep.2024.113881. Epub ahead of print. PMID: 38442019.

Ginwala R, Caruso B, Khan ZK, Pattekar A, Chew GM, Corley MJ, Loonawat R, Jacobson S, Sreedhar S, Ndhlovu LC, Jain P. HTLV-1 Infection and Neuropathogenesis in the Context of Rag1-/-γc-/-(RAG1-Hu) and BLT Mice. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. 2017 September;12(3):504-520. PubMed PMID: 28374110; PubMed Central PMCID: PMC5529230.

Lee RWY, Corley MJ, Pang A, Arakaki G, Abbott L, Nishimoto M, Miyamoto R, Lee E, Yamamoto S, Maunakea AK, Lum-Jones A, Wong M. A modified ketogenic gluten-free diet with MCT improves behavior in children with autism spectrum disorder. Physiology Behavior. 2018 May 1;188:205-211. PubMed PMID: 29421589; PubMed Central PMCID: PMC5863039.

Uzzan M, Tokuyama M, Rosenstein AK, Tomescu C, SahBandar IN, Ko HM, Leyre L, Chokola A, Kaplan-Lewis E, Rodriguez G, Seki A, Corley MJ, Aberg J, La Porte A, Park EY, Ueno H, Oikonomou I, Doron I, Iliev ID, Chen BK, Lui J, Schacker TW, Furtado GC, Lira SA, Colombel JF, Horowitz A, Lim JK, Chomont N, Rahman AH, Montaner LJ, Ndhlovu LC, Mehandru S. Anti-α4β7 therapy targets lymphoid aggregates in the gastrointestinal tract of HIV-1-infected individuals. Science translational medicine. 2018 October 3;10(461). PubMed PMID: 30282696; PubMed Central PMCID: PMC6314200; DOI: 10.1126/scitranslmed.aau4711.

Zhang X, Hu Y, Aouizerat BE, Peng G, Marconi VC, Corley MJ, Hulgan T, Bryant KJ, Zhao H, Krystal JH, Justice AC, Xu K. Machine learning selected smoking-associated DNA methylation signatures that predict HIV prognosis and mortality. Clinical epigenetics. 2018 December 13;10(1):155. PubMed PMID: 30545403; PubMed Central PMCID: PMC6293604; DOI: 10.1186/s13148-018-0591-z.

Balaan C, Corley MJ, Eulalio T, Leite-Ahyo K, Pang APS, Fang R, Khadka VS, Maunakea AK, Ward MA. Juvenile Shank3b deficient mice present with behavioral phenotype relevant to autism spectrum disorder. Behavioural brain research. 2019 January 1;356:137-147. PubMed PMID: 30134148; PubMed Central PMCID: PMC6247805; DOI: 10.1016/j.bbr.2018.08.005.

Dye CK, Corley MJ, Li D, Khadka VS, Mitchell BI, Sultana R, Lum-Jones A, Shikuma CM, Ndhlovu LC, Maunakea AK. Comparative DNA methylomic analyses reveal potential origins of novel epigenetic biomarkers of insulin resistance in monocytes from virally suppressed HIV-infected adults. Clinical epigenetics. 2019 June 28;11(1):95. PubMed PMID: 31253200; PubMed Central PMCID: PMC6599380; DOI: 10.1186/s13148-019-0694-1.

Fujimoto BA, Young M, Carter L, Pang APS, Corley MJ, Fogelgren B, Polgar N. The exocyst complex regulates insulin-stimulated glucose uptake of skeletal muscle cells. Am J Physiol Endocrinol Metab. 2019 Dec 1;317(6):E957-E972. doi: 10.1152/ajpendo.00109.2019. Epub 2019 Oct 8. PMID:31593505.

Corley MJ, Vargas-Maya N, Pang APS, Lum-Jones A, Li D, Khadka V, Sultana R, Blanchard DC, Maunakea AK. Epigenetic Delay in the Neurodevelopmental Trajectory of DNA Methylation States in Autism Spectrum Disorders. Frontiers in genetics. 2019;10:907. PubMed PMID: 31681403; PubMed Central PMCID: PMC6797928; DOI: 10.3389/fgene.2019.00907.

D’Antoni ML, Kallianpur KJ, Premeaux TA, Corley MJ, Fujita T, Laws EI, Ogata-Arakaki D, Chow DC, Khadka VS, Shikuma CM, Ndhlovu LC. Lower Interferon Regulatory Factor-8 Expression in Peripheral Myeloid Cells Tracks With Adverse Central Nervous System Outcomes in Treated HIV Infection. Frontiers in immunology. 2019;10:2789. PubMed PMID: 31849969; PubMed Central PMCID: PMC6895026; DOI: 10.3389/fimmu.2019.02789.

Mu C, Corley MJ, Lee RWY, Wong M, Pang A, Arakaki G, Miyamoto R, Rho JM, Mickiewicz B, Dowlatabadi R, Vogel HJ, Korchemagin Y, Shearer J. Metabolic Framework for the Improvement of Autism Spectrum Disorders by a Modified Ketogenic Diet: A Pilot Study. J Proteome Res. 2020 Jan 3;19(1):382-390. doi: 10.1021/acs.jproteome.9b00581. Epub 2019 Nov 22. PMID: 31696714.

Patterson BK, Seethamraju H, Dhody K, Corley MJ, Kazempour K, Lalezari JP, Pang AP, Sugai C, Francisco EB, Pise A, Rodrigues H, Ryou M, Wu HL, Webb GM, Park BS, Kelly S, Pourhassan N, Lelic A, Kdouh L, Herrera M, Hall E, Aklin E, Ndhlovu L, Sacha JB. Disruption of the CCL5/RANTES-CCR5 Pathway Restores Immune Homeostasis and Reduces Plasma Viral Load in Critical COVID-19. medRxiv [Preprint]. 2020 May 5:2020.05.02.20084673. doi: 10.1101/2020.05.02.20084673. PMID: 32511656; PMCID: PMC7277012.

Premeaux TA, Javandel S, Hosaka KRJ, Greene M, Therrien N, Allen IE, Corley MJ, Valcour VG, Ndhlovu LC. Associations Between Plasma Immunomodulatory and Inflammatory Mediators With VACS Index Scores Among Older HIV-Infected Adults on Antiretroviral Therapy. Front Immunol. 2020 Jun 30;11:1321. doi: 10.3389/fimmu.2020.01321. PMID: 32695109; PMCID: PMC7338430.

Go RCP, Corley MJ, Ross GW, Petrovitch H, Masaki KH, Maunakea AK, He Q, Tiirikainen MI. Genome-wide epigenetic analyses in Japanese immigrant plantation workers with Parkinson’s disease and exposure to organochlorines reveal possible involvement of glial genes and pathways involved in neurotoxicity. BMC Neurosci. 2020 Jul 10;21(1):31. doi: 10.1186/s12868-020-00582-4. PMID: 32650713; PMCID: PMC7350633.

SahBandar IN, Chew GM, Corley MJ, Pang APS, Tsai N, Hanks N, Khadka VS, Klatt NR, Hensley-McBain T, Somsouk M, Vujkovic-Cvijin I, Chow DC, Shikuma CM, Ndhlovu LC. Changes in gastrointestinal microbial communities influence HIV-specific CD8+ T-cell responsiveness to immune checkpoint blockade. AIDS. 2020 Aug 1;34(10):1451-1460. doi: 10.1097/QAD.0000000000002557. PMID: 32675558; PMCID: PMC7371239.

Patterson BK, Seethamraju H, Dhody K, Corley MJ, Kazempour K, Lalezari J, Pang APS, Sugai C, Mahyari E, Francisco EB, Pise A, Rodrigues H, Wu HL, Webb GM, Park BS, Kelly S, Pourhassan N, Lelic A, Kdouh L, Herrera M, Hall E, Bimber BN, Plassmeyer M, Gupta R, Alpan O, O’Halloran JA, Mudd PA, Akalin E, Ndhlovu LC, Sacha JB. CCR5 inhibition in critical COVID-19 patients decreases inflammatory cytokines, increases CD8 T-cells, and decreases SARS-CoV2 RNA in plasma by day 14. Int J Infect Dis. 2020 Nov 10;103:25-32. doi: 10.1016/j.ijid.2020.10.101. Epub ahead of print. PMID: 33186704; PMCID: PMC7654230.

Suárez-Fariñas M, Tokuyama M, Wei G, Huang R, Livanos A, Jha D, Levescot A, Irizar H, Kosoy R, Cording S, Wang W, Losic B, Ungaro RC, Di’Narzo A, Martinez-Delgado G, Suprun M, Corley MJ, Stojmirovic A, Houten SM, Peters L, Curran M, Brodmerkel C, Perrigoue J, Friedman JR, Hao K, Schadt EE, Zhu J, Ko HM, Cho J, Dubinsky MC, Sands BE, Ndhlovu L, Cerf-Bensusan N, Kasarskis A, Colombel JF, Harpaz N, Argmann C, Mehandru S. Intestinal Inflammation Modulates the Expression of ACE2 and TMPRSS2 and Potentially Overlaps With the Pathogenesis of SARS-CoV-2-related Disease. Gastroenterology. 2021 Jan;160(1):287-301.e20. doi: 10.1053/j.gastro.2020.09.029. Epub 2020 Sep 25. PMID: 32980345; PMCID: PMC7516468.

Chew GM, Padua AJP, Chow DC, Souza SA, Clements DM, Corley MJ, Pang APS, Alejandria MM, Gerschenson M, Shikuma CM, Ndhlovu LC. Effects of Brief Adjunctive Metformin Therapy in Virologically Suppressed HIV-Infected Adults on Polyfunctional HIV-Specific CD8 T Cell Responses to PD-L1 Blockade. AIDS research and human retroviruses. 2021 January;37(1):24-33. PubMed PMID: 33019813; PubMed Central PMCID: PMC7864091; DOI: 10.1089/AID.2020.0172.

Corley MJ, Pang APS, Dody K, Mudd PA, Patterson BK, Seethamraju H, Bram Y, Peluso MJ, Torres L, Iyer NS, Premeaux TA, Yeung ST, Chandar V, Borczuk A, Schwartz RE, Henrich TJ, Deeks SG, Sacha JB, Ndhlovu LC. Genome-wide DNA methylation profiling of peripheral blood reveals an epigenetic signature associated with severe COVID-19. J Leukoc Biol. 2021 Jan 19. doi: 10.1002/JLB.5HI0720-466R. Epub ahead of print. PMID: 33464637.

Corley MJ, Sacdalan C, Pang APS, Chomchey N, Ratnaratorn N, Valcour V, Kroon E, Cho KS, Belden AC, Colby D, Robb M, Hsu D, Spudich S, Paul R, Vasan S, Ndhlovu LC; SEARCH010/RV254 and SEARCH013/RV304 study groups. Abrupt and altered cell-type specific DNA methylation profiles in blood during acute HIV infection persists despite prompt initiation of ART. PLoS Pathog. 2021 Aug 13;17(8):e1009785. doi: 10.1371/journal.ppat.1009785. PMID: 34388205; PMCID: PMC8386872.

Corley MJ, Pang APS, Rasmussen TA, Tolstrup M, Søgaard OS, Ndhlovu LC. Candidate host epigenetic marks predictive for HIV reservoir size, responsiveness to latency reversal, and viral rebound. AIDS. 2021 Nov 15;35(14):2269-2279. doi: 10.1097/QAD.0000000000003065. PMID: 34482353; PMCID: PMC8563431.

Corley MJ, Farhadian SF. Emerging Single-cell Approaches to Understand HIV in the Central Nervous System. Curr HIV/AIDS Rep. 2022 Feb;19(1):113-120. doi: 10.1007/s11904-021-00586-7. Epub 2021 Nov 25. PMID: 34822063; PMCID: PMC8613726.

Plassmeyer M, Alpan O, Corley MJ, Premeaux TA, Lillard K, Coatney P, Vaziri T, Michalsky S, Pang APS, Bukhari Z, Yeung ST, Evering TH, Naughton G, Latterich M, Mudd P, Spada A, Rindone N, Loizou D, Ulrik Sønder S, Ndhlovu LC, Gupta R. Caspases and therapeutic potential of caspase inhibitors in moderate-severe SARS-CoV-2 infection and long COVID. Allergy. 2022 Jan;77(1):118-129. doi: 10.1111/all.14907. Epub 2021 Jun 2. PMID: 33993490; PMCID: PMC8222863.

Premeaux TA, Moser CB, McKhann A, Hoenigl M, Yeung ST, Pang APS, Corley MJ, Lederman MM, Landay AL, Gianella S, Ndhlovu LC. Monitoring Circulating Immune Checkpoint Proteins as Predictors of Non-AIDS Morbid Events in People With HIV Initiating Antiretroviral Therapy. Open Forum Infect Dis. 2022 Jan 21;9(3):ofab570. doi: 10.1093/ofid/ofab570. PMID: 35146038; PMCID: PMC8826032.

Corley MJ, Yokoyama JS. Candidate Epigenetic Biomarker of Cognitive Trajectory: The Chicken or the Egg? Biol Psychiatry. 2022 Feb 15;91(4):332-334. doi: 10.1016/j.biopsych.2021.11.014. PMID: 35057971.

Hsu DC, Chumpolkulwong K, Corley MJ, Hunsawong T, Inthawong D, Schuetz A, Imerbsin R, Silsorn D, Nadee P, Sopanaporn J, Phuang-Ngern Y, Klungthong C, Reed M, Fernandez S, Ndhlovu LC, Paul R, Lugo-Roman L, Michael NL, Modjarrad K, Vasan S. Neurocognitive impact of Zika virus infection in adult rhesus macaques. J Neuroinflammation. 2022 Feb 7;19(1):40. doi: 10.1186/s12974-022-02402-4. PMID: 35130924; PMCID: PMC8822695.

Chang XL, Reed JS, Webb GM, Wu HL, Le J, Bateman KB, Greene JM, Pessoa C, Waytashek C, Weber WC, Hwang J, Fischer M, Moats C, Shiel O, Bochart RM, Crank H, Siess D, Giobbi T, Torgerson J, Agnor R, Gao L, Dhody K, Lalezari JP, Bandar IS, Carnate AM, Pang AS, Corley MJ, Kelly S, Pourhassan N, Smedley J, Bimber BN, Hansen SG, Ndhlovu LC, Sacha JB. Suppression of human and simian immunodeficiency virus replication with the CCR5-specific antibody Leronlimab in two species. PLoS Pathog. 2022 Mar 31;18(3):e1010396. doi: 10.1371/journal.ppat.1010396. PMID: 35358290; PMCID: PMC8970399.

Rathnasinghe R, Jangra S, Ye C, Cupic A, Singh G, Martínez-Romero C, Mulder LCF, Kehrer T, Yildiz S, Choi A, Yeung ST, Mena I, Gillespie V, De Vrieze J, Aslam S, Stadlbauer D, Meekins DA, McDowell CD, Balaraman V, Corley MJ, Richt JA, De Geest BG, Miorin L; PVI study group, Krammer F, Martinez-Sobrido L, Simon V, García-Sastre A, Schotsaert M. Characterization of SARS-CoV-2 Spike mutations important for infection of mice and escape from human immune sera. Nat Commun. 2022 Jul 7;13(1):3921. doi: 10.1038/s41467-022-30763-0. PMID: 35798721; PMCID: PMC9261898.

Farhadian SF, Lindenbaum O, Zhao J, Corley MJ, Im Y, Walsh H, Vecchio A, Garcia-Milian R, Chiarella J, Chintanaphol M, Calvi R, Wang G, Ndhlovu LC, Yoon J, Trotta D, Ma S, Kluger Y, Spudich S. HIV viral transcription and immune perturbations in the CNS of people with HIV despite ART. JCI Insight. 2022 Jul 8;7(13):e160267. doi: 10.1172/jci.insight.160267. PMID: 35801589.

Pang APS, Higgins-Chen AT, Comite F, Raica I, Arboleda C, Went H, Mendez T, Schotsaert M, Dwaraka V, Smith R, Levine ME, Ndhlovu LC, Corley MJ. Longitudinal Study of DNA Methylation and Epigenetic Clocks Prior to and Following Test-Confirmed COVID-19 and mRNA Vaccination. Front Genet. 2022 Jun 3;13:819749. doi: 10.3389/fgene.2022.819749. PMID: 35719387; PMCID: PMC9203887.

Dye CK, Corley MJ, Ing C, Lum-Jones A, Li D, Mau MKLM, Maunakea AK. Shifts in the immunoepigenomic landscape of monocytes in response to a diabetes-specific social support intervention: a pilot study among Native Hawaiian adults with diabetes. Clin Epigenetics. 2022 Jul 18;14(1):91. doi: 10.1186/s13148-022-01307-6. PMID: 35851422; PMCID: PMC9295496.

Kroll KW, Shah SV, Lucar OA, Premeaux TA, Shikuma CM, Corley MJ, Mosher M, Woolley G, Bowler S, Ndhlovu LC, Reeves RK. Mucosal-homing natural killer cells are associated with aging in persons living with HIV. Cell Rep Med. 2022 Oct 18;3(10):100773. doi: 10.1016/j.xcrm.2022.100773. Epub 2022 Oct 7. PMID: 36208628; PMCID: PMC9589002.

Bowler S, Papoutsoglou G, Karanikas A, Tsamardinos I, Corley MJ, Ndhlovu LC. A machine learning approach utilizing DNA methylation as an accurate classifier of COVID-19 disease severity. Sci Rep. 2022 Oct 19;12(1):17480. doi: 10.1038/s41598-022-22201-4. PMID: 36261477; PMCID: PMC9580434.

Kong W, Montano M, Corley MJ, Helmy E, Kobayashi H, Kinisu M, Suryawanshi R, Luo X, Royer LA, Roan NR, Ott M, Ndhlovu LC, Greene WC. Neuropilin-1 Mediates SARS-CoV-2 Infection of Astrocytes in Brain Organoids, Inducing Inflammation Leading to Dysfunction and Death of Neurons. mBio. 2022 Oct 31;13(6):e0230822. doi: 10.1128/mbio.02308-22. Epub ahead of print. PMID: 36314791; PMCID: PMC9765283.

Santamaria-Garcia H, Moguilner S, Rodriguez-Villagra OA, Botero-Rodriguez F, Pina-Escudero SD, O’Donovan G, Albala C, Matallana D, Schulte M, Slachevsky A, Yokoyama JS, Possin K, Ndhlovu LC, Al-Rousan T, Corley MJ, Kosik KS, Muniz-Terrera G, Miranda JJ, Ibanez A. The impacts of social determinants of health and cardiometabolic factors on cognitive and functional aging in Colombian underserved populations. Geroscience. 2023 Feb 28. doi: 10.1007/s11357-023-00755-z. Epub ahead of print. PMID: 36849677.

Kroll KW, Woolley G, Terry K, Premeaux TA, Shikuma CM, Corley MJ, Bowler S, Ndhlovu LC, Reeves RK. Multiplex analysis of cytokines and chemokines in persons aging with or without HIV. bioRxiv [Preprint]. 2023 Feb 2:2023.01.30.526135. doi: 10.1101/2023.01.30.526135. Update in: AIDS Res Hum Retroviruses. 2023 Apr 25;: PMID: 36778301; PMCID: PMC9915515.

Kroll KW, Woolley G, Terry K, Premeaux TA, Shikuma CM, Corley MJ, Bowler S, Ndhlovu LC, Reeves RK. Multiplex Analysis of Cytokines and Chemokines in Persons Aging With or Without HIV. AIDS Res Hum Retroviruses. 2023 Jul;39(7):367-380. doi: 10.1089/AID.2022.0183. Epub 2023 Jun 7. PMID: 37097212.

Ortiz-Whittingham LR, Baumer Y, Pang APS, Sampson M, Baez AS, Rose RR, Noonan SH, Mendez-Silva J, Collins BS, Mitchell VM, Cintron MA, Farmer N, Remaley AT, Corley MJ, Powell-Wiley TM. Associations between neighborhood socioeconomic deprivation, IFNγ, and high-density lipoprotein particle size: Data from the Washington, D.C. cardiovascular health and needs assessment. Psychoneuroendocrinology. 2023 Nov;157:106346. doi: 10.1016/j.psyneuen.2023.106346. Epub 2023 Aug 9. PMID: 37651859; PMCID: PMC10543547.

Santamaria-Garcia H, Sainz-Ballesteros A, Hernandez H, Moguilner S, Maito M, Ochoa-Rosales C, Corley M, Valcour V, Miranda JJ, Lawlor B, Ibanez A. Factors associated with healthy aging in Latin American populations. Nat Med. 2023 Sep;29(9):2248-2258. doi: 10.1038/s41591-023-02495-1. Epub 2023 Aug 10. PMID: 37563242; PMCID: PMC10504086.

Schuetz A, Corley MJ, Sacdalan C, Phuang-Ngern Y, Nakpor T, Wansom T, Ehrenberg PK, Sriplienchan S, Thomas R, Ratnaratorn N, Sukhumvittaya S, Tragonlugsana N, Slike BM, Akapirat S, Pinyakorn S, Rerknimitr R, Pang AP, Kroon E, Teeratakulpisan N, Krebs SJ, Phanuphak N, Ndhlovu LC, Vasan S; RV304/SEARCH013 Study Team. Distinct mucosal and systemic immunological characteristics in transgender women potentially relating to HIV acquisition. JCI Insight. 2023 Aug 22;8(16):e169272. doi: 10.1172/jci.insight.169272. PMID: 37432754; PMCID: PMC10543719.

Promsote W, Chumpolkulwong K, Musich T, Corley MJ, Ndhlovu LC, Sopanaporn J, Inthawong D, Nadee P, Silsorn D, Sirisrisopa S, Wongsawanonkul S, Parsons MS, Cowden J, Imerbsin R, Lugo-Roman L, Vasan S, Hsu DC. Impact of sleep deprivation on neurocognition and inflammation in rhesus macaques. Brain Behav Immun Health. 2023 Sep 1;33:100683. doi: 10.1016/j.bbih.2023.100683. PMID: 37701789; PMCID: PMC10493883.

Corley MJ, Pang APS, Shikuma CM, Ndhlovu LC. Cell-type specific impact of metformin on monocyte epigenetic age reversal in virally suppressed older people living with HIV. Aging Cell. 2024 Jan;23(1):e13926. doi: 10.1111/acel.13926. Epub 2023 Sep 7. PMID: 37675817; PMCID: PMC10776116.

Copertino DC Jr, Holmberg CS, Weiler J, Ward AR, Howard JN, Levinger C, Pang AP, Corley MJ, Dündar F, Zumbo P, Betel D, Gandhi RT, McMahon DK, Bosch RJ, Linden N, Macatangay BJ, Cyktor JC, Eron JJ, Mellors JW, Kovacs C, Benko E, Bosque A, Jones RB; AIDS Clinical Trials Group (ACTG) A5321 Team. The latency-reversing agent HODHBt synergizes with IL-15 to enhance cytotoxic function of HIV-specific T cells. JCI Insight. 2023 Sep 22;8(18):e169028. doi: 10.1172/jci.insight.169028. PMID: 37581929; PMCID: PMC10561764.

Ndhlovu LC, Bendall ML, Dwaraka V, Pang AP, Dopkins N, Carreras N, Smith R, Nixon DF, Corley MJ. Retroelement-Age Clocks: Epigenetic Age Captured by Human Endogenous Retrovirus and LINE-1 DNA methylation states. bioRxiv [Preprint]. 2023 Dec 7:2023.12.06.570422. doi: 10.1101/2023.12.06.570422. PMID: 38106164; PMCID: PMC10723416.

Lee E, Carreras-Gallo N, Lopez L, Turner L, Lin A, Mendez TL, Went H, Tomusiak A, Verdin E, Corley M, Ndhlovu L, Smith R, Dwaraka VB. Exploring the effects of Dasatinib, Quercetin, and Fisetin on DNA methylation clocks: a longitudinal study on senolytic interventions. Aging (Albany NY). 2024 Feb 22;16(4):3088-3106. doi: 10.18632/aging.205581. Epub 2024 Feb 22. PMID: 38393697.

Singh S, Giron LB, Shaikh MW, Shankaran S, Engen PA, Bogin ZR, Bambi SA, Goldman AR, Azevedo JLLC, Orgaz L, de Pedro N, González P, Giera M, Verhoeven A, Sánchez-López E, Pandrea I, Kannan T, Tanes CE, Bittinger K, Landay AL, Corley MJ, Keshavarzian A, Abdel-Mohsen M. Distinct intestinal microbial signatures linked to accelerated systemic and intestinal biological aging. Microbiome. 2024 Feb 22;12(1):31. doi: 10.1186/s40168-024-01758-4. PMID: 38383483; PMCID: PMC10882811.

Singh S, Giron LB, Shaikh MW, Shankaran S, Engen PA, Bogin ZR, Bambi SA, Goldman AR, Azevedo JLLC, Orgaz L, de Pedro N, González P, Giera M, Verhoeven A, Sánchez-López E, Pandrea IV, Kannan T, Tanes CE, Bittinger K, Landay AL, Corley MJ, Keshavarzian A, Abdel-Mohsen M. Distinct Intestinal Microbial Signatures Linked to Accelerated Biological Aging in People with HIV. Res Sq [Preprint]. 2023 Oct 30:rs.3.rs-3492242. doi: 10.21203/rs.3.rs-3492242/v1. Update in: Microbiome. 2024 Feb 22;12(1):31. PMID: 37961645; PMCID: PMC10635386.

Berry M, Chen J, Hixon A, Gerschenson M, James N, Jameson D, Lew HL, Lozanoff S, Nichols R, Seifried S, Teshima D, Masaki K, Tam E, Ward B, Ward S. Medical School Hotline: School of Medicine Departments – Year in Review 2017, Part 1. Hawaii journal of medicine & public health : a journal of Asia Pacific Medicine & Public Health. 2018 January;77(1):14-16. PubMed PMID: 29333336; PubMed Central PMCID: PMC5760310.

Goo BMSS, Sanstrum BJ, Holden DZY, Yu Y, James NG. Arc/Arg3.1 has an activity- regulated interaction with PICK1 that results in altered spatial dynamics. Scientific reports. 2018 October 2;8(1):14675. PubMed PMID: 30279480; PubMed Central PMCID: PMC6168463; DOI: 10.1038/s41598-018-32821-4.

Gallea JI, Ambroggio EE, Vilcaes AA, James NG, Jameson DM, Celej MS. Amyloid oligomerization of the Parkinson’s disease related protein α-synuclein impacts on its curvature-membrane sensitivity. Journal of neurochemistry. 2018 November 6;147(4):541-556. PubMed PMID: 30142705; DOI: 10.1111/jnc.14573.

Nguyen H, Ward WS, James NG. Spatial and temporal resolution of mORC4 fluorescent variants reveals structural requirements for achieving higher order self-association and pronuclei entry. Methods and applications in fluorescence. 2019 May 16;7(3):035002. PubMed PMID: 30865939; DOI: 10.1088/2050-6120/ab0f57.

Sanstrum BJ, Goo BMSS, Holden DZY, Delgado DD, Nguyen TPN, Lee KD, James NG. Fluctuation Imaging of LRRK2 Reveals that the G2019S Mutation Alters Spatial and Membrane Dynamics. Molecules (Basel, Switzerland). 2020 May 31;25(11). PubMed PMID: 32486414; PubMed Central PMCID: PMC7321188; DOI: 10.3390/molecules25112561.

James NG, Malik S, Sanstrum BJ, Rhéaume C, Broide RS, Jameson DM, Brideau-Andersen A, Jacky BS. Characterization of clostridium botulinum neurotoxin serotype A (BoNT/A) and fibroblast growth factor receptor interactions using novel receptor dimerization assay. Sci Rep. 2021 Apr 9;11(1):7832. doi: 10.1038/s41598-021-87331-7. PMID: 33837264; PMCID: PMC8035261.

Dow A, Sule P, O’Donnell TJ, Burger A, Mattila JT, Antonio B, Vergara K, Marcantonio E, Adams LG, James N, Williams PG, Cirillo JD, Prisic S. Zinc limitation triggers anticipatory adaptations in Mycobacterium tuberculosis. PLoS pathogens. 2021 May;17(5):e1009570. PubMed PMID: 33989345; DOI: 10.1371/journal.ppat.1009570.

Meng D, Yang Q, Melick CH, Park BC, Hsieh TS, Curukovic A, Jeong MH, Zhang J, James NG, Jewell JL. ArfGAP1 inhibits mTORC1 lysosomal localization and activation. The EMBO journal. 2021 May 14:e106412. PubMed PMID: 33988249; DOI: 10.15252/embj.2020106412.

Servetto A, Kollipara R, Formisano L, Lin CC, Lee KM, Sudhan DR, Gonzalez-Ericsson PI, Chatterjee S, Guerrero-Zotano A, Mendiratta S, Akamatsu H, James N, Bianco R, Hanker AB, Kittler R, Arteaga CL. Nuclear FGFR1 Regulates Gene Transcription and Promotes Antiestrogen Resistance in ER+ Breast Cancer. Clin Cancer Res. 2021 Aug 1;27(15):4379-4396. doi: 10.1158/1078-0432.CCR-20-3905. Epub 2021 May 19. PMID: 34011560; PMCID: PMC8338892.

Zhang S, Wang H, Melick CH, Jeong MH, Curukovic A, Tiwary S, Lama-Sherpa TD, Meng D, Servage KA, James NG, Jewell JL. AKAP13 couples GPCR signaling to mTORC1 inhibition. PLoS Genet. 2021 Oct 21;17(10):e1009832. doi: 10.1371/journal.pgen.1009832. PMID: 34673774; PMCID: PMC8570464.

Tassin TC, Barylko B, Hedde PN, Chen Y, Binns DD, James NG, Mueller JD, Jameson DM, Taussig R, Albanesi JP. Gain-of-Function Properties of a Dynamin 2 Mutant Implicated in Charcot-Marie-Tooth Disease. Front Cell Neurosci. 2021 Oct 20;15:745940. doi: 10.3389/fncel.2021.745940. PMID: 34744632; PMCID: PMC8563704.

Lynch JB, James N, McFall-Ngai M, Ruby EG, Shin S, Takagi D. Transitioning to confined spaces impacts bacterial swimming and escape response. Biophys J. 2022 Jul 5;121(13):2653-2662. doi: 10.1016/j.bpj.2022.04.008. Epub 2022 Apr 6. PMID: 35398019.

Polgar N, Fogelgren B. Regulation of Cell Polarity by Exocyst-Mediated Trafficking. Cold Spring Harb Perspect Biol. 2018 Mar 1;10(3):a031401. doi: 10.1101/cshperspect.a031401. PMID: 28264817; PMCID: PMC5587355.

Fujimoto BA, Young M, Carter L, Pang APS, Corley MJ, Fogelgren B, Polgar N. The exocyst complex regulates insulin-stimulated glucose uptake of skeletal muscle cells. Am J Physiol Endocrinol Metab. 2019 Dec 1;317(6):E957-E972. doi: 10.1152/ajpendo.00109.2019. Epub 2019 Oct 8. PMID:31593505.

Zuo X, Kwon SH, Janech MG, Dang Y, Lauzon SD, Fogelgren B, Polgar N, Lipschutz JH. Primary cilia and the exocyst are linked to urinary extracellular vesicle production and content. The Journal of biological chemistry. 2019 December 13;294(50):19099-19110. PubMed PMID: 31694916; PubMed Central PMCID: PMC6916495; DOI: 10.1074/jbc.RA119.009297.

Fujimoto BA, Young M, Nakamura N, Ha H, Carter L, Pitts MW, Torres D, Noh HL, Suk S, Kim JK, Polgar N. Disrupted glucose homeostasis and skeletal muscle-specific glucose uptake in an exocyst knockout mouse model. The Journal of biological chemistry. 2021 February 26:100482. PubMed PMID: 33647317; PubMed Central PMCID: PMC8027262; DOI: 10.1016/j.jbc.2021.100482.

Nakamura NK, Tokunaga DS, Ha HY, Polgar N. The Exocyst Is Required for CD36 Fatty Acid Translocase Trafficking and Free Fatty Acid Uptake in Skeletal Muscle Cells. Cells. 2022 Aug 6;11(15):2440. doi: 10.3390/cells11152440. PMID: 35954283; PMCID: PMC9368548.

Dedinszki D, Szeri F, Kozák E, Pomozi V, Tőkési N, Mezei TR, Merczel K, Letavernier E, Tang E, Le Saux O, Arányi T, van de Wetering K, Váradi A. Oral administration of pyrophosphate inhibits connective tissue calcification. EMBO molecular medicine. 2017 November;9(11):1463-1470. PubMed PMID: 28701330; PubMed Central PMCID: PMC5666306.

Bauer C, Le Saux O, Pomozi V, Aherrahrou R, Kriesen R, Stölting S, Liebers A, Kessler T, Schunkert H, Erdmann J, Aherrahrou Z. Etidronate prevents dystrophic cardiac calcification by inhibiting macrophage aggregation. Scientific reports. 2018 April 11;8(1):5812. PubMed PMID: 29643466; PubMed Central PMCID: PMC5895639.

Kauffenstein G, Yegutkin GG, Khiati S, Pomozi V, Le Saux O, Leftheriotis G, Lenaers G, Henrion D, Martin L. Alteration of Extracellular Nucleotide Metabolism in Pseudoxanthoma Elasticum. The Journal of investigative dermatology. 2018 August;138(8):1862-1870. PubMed PMID: 29501384; DOI: 10.1016/j.jid.2018.02.023.

Letavernier E, Kauffenstein G, Huguet L, Navasiolava N, Bouderlique E, Tang E, Delaitre L, Bazin D, de Frutos M, Gay C, Perez J, Verpont MC, Haymann JP, Pomozi V, Zoll J, Le Saux O, Daudon M, Leftheriotis G, Martin L. ABCC6 Deficiency Promotes Development of Randall Plaque. Journal of the American Society of Nephrology : JASN. 2018 September;29(9):2337-2347. PubMed PMID: 29991491; PubMed Central PMCID: PMC6115671; DOI: 10.1681/ASN.2017101148.

Pomozi V, Julian CB, Zoll J, Pham K, Kuo S, Tőkési N, Martin L, Váradi A, Le Saux O. Dietary Pyrophosphate Modulates Calcification in a Mouse Model of Pseudoxanthoma Elasticum: Implication for Treatment of Patients. The Journal of investigative dermatology. 2019 May;139(5):1082-1088. PubMed PMID: 30468740; PubMed Central PMCID: PMC6478508; DOI: 10.1016/j.jid.2018.10.040.

Panee J, Pomozi V, Franke AA, Le Saux O, Gerschenson M. Chronic marijuana use moderates the correlations of serum cholesterol with systemic mitochondrial function and fluid cognition. Mitochondrion. 2020 May;52:135-143. PubMed PMID: 32169611; PubMed Central PMCID: PMC8041574; DOI: 10.1016/j.mito.2020.03.006.

Kozák E, Szikora B, Iliás A, Jani PK, Hegyi Z, Matula Z, Dedinszki D, Tőkési N, Fülöp K, Pomozi V, Várady G, Bakos É, Tusnády GE, Kacskovics I, Váradi A. Creation of the first monoclonal antibody recognizing an extracellular epitope of hABCC6. FEBS Lett. 2020 Nov 7. doi: 10.1002/1873-3468.13991. Epub ahead of print. PMID: 33159684.

Tőkési N, Kozák E, Fülöp K, Dedinszki D, Hegedűs N, Király B, Szigeti K, Ajtay K, Jakus Z, Zaworski J, Letavernier E, Pomozi V, Váradi A. Pyrophosphate therapy prevents trauma-induced calcification in the mouse model of neurogenic heterotopic ossification. J Cell Mol Med. 2020 Oct;24(20):11791-11799. doi: 10.1111/jcmm.15793. Epub 2020 Sep 4. PMID: 32885586; PMCID: PMC7579705.

Brampton C, Pomozi V, Chen LH, Apana A, McCurdy S, Zoll J, Boisvert WA, Lambert G, Henrion D, Blanchard S, Kuo S, Leftheriotis G, Martin L, Le Saux O. ABCC6 deficiency promotes dyslipidemia and atherosclerosis. Scientific reports. 2021 February 16;11(1):3881. PubMed PMID: 33594095; PubMed Central PMCID: PMC7887252; DOI: 10.1038/s41598-021-82966-y.

Shimada BK, Pomozi V, Zoll J, Kuo S, Martin L, Le Saux O. ABCC6, Pyrophosphate and Ectopic Calcification: Therapeutic Solutions. International journal of molecular sciences. 2021 April 27;22(9). PubMed PMID: 33925341; PubMed Central PMCID: PMC8123679; DOI: 10.3390/ijms22094555.

Kozák E, Fülöp K, Tőkési N, Rao N, Li Q, Terry SF, Uitto J, Zhang X, Becker C, Váradi A, Pomozi V. Oral supplementation of inorganic pyrophosphate in pseudoxanthoma elasticum. Exp Dermatol. 2022 Apr;31(4):548-555. doi: 10.1111/exd.14498. Epub 2021 Nov 17. PMID: 34758173; PMCID: PMC8977233.

Kozák E, Bartstra JW, de Jong PA, Mali WPTM, Fülöp K, Tőkési N, Pomozi V, Risseeuw S, Norel JO, van Leeuwen R, Váradi A, Spiering W. Plasma Level of Pyrophosphate Is Low in Pseudoxanthoma Elasticum Owing to Mutations in the ABCC6 Gene, but It Does Not Correlate with ABCC6 Genotype. J Clin Med. 2023 Jan 29;12(3):1047. doi: 10.3390/jcm12031047. PMID: 36769695; PMCID: PMC9917606.

Brampton C, Pomozi V, Le Corre Y, Zoll J, Kauffenstein G, Ma C, Hoffmann PR, Martin L, Le Saux O. Bone Marrow-Derived ABCC6 Is an Essential Regulator of Ectopic Calcification In PXE. J Invest Dermatol. 2024 Feb 15:S0022-202X(24)00110-6. doi: 10.1016/j.jid.2024.01.026. Epub ahead of print. PMID: 38367909.

Horowitz LF, Rodriguez AD, Ray T, Folch A. Microfluidics for interrogating live intact tissues. Microsyst Nanoeng. 2020 Aug 24;6:69. doi: 10.1038/s41378-020-0164-0. PMID: 32879734; PMCID: PMC7443437.

Hourlier-Fargette A, Schon S, Xue Y, Avila R, Li W, Gao Y, Liu C, Kim SB, Raj MS, Fields KB, Parsons BV, Lee K, Lee JY, Chung HU, Lee SP, Johnson M, Bandodkar AJ, Gutruf P, Model JB, Aranyosi AJ, Choi J, Ray TR, Ghaffari R, Huang Y, Rogers JA. Skin-interfaced soft microfluidic systems with modular and reusable electronics for in situ capacitive sensing of sweat loss, rate and conductivity. Lab Chip. 2020 Nov 24;20(23):4391-4403. doi: 10.1039/d0lc00705f. PMID: 33089837.

Ray TR, Ivanovic M, Curtis PM, Franklin D, Guventurk K, Jeang WJ, Chafetz J, Gaertner H, Young G, Rebollo S, Model JB, Lee SP, Ciraldo J, Reeder JT, Hourlier-Fargette A, Bandodkar AJ, Choi J, Aranyosi AJ, Ghaffari R, McColley SA, Haymond S, Rogers JA. Soft, skin-interfaced sweat stickers for cystic fibrosis diagnosis and management. Science translational medicine. 2021 March 31;13(587). PubMed PMID: 33790027; DOI: 10.1126/scitranslmed.abd8109.

Ghaffari R, Rogers JA, Ray TR. Recent progress, challenges, and opportunities for wearable biochemical sensors for sweat analysis. Sensors and actuators. B, Chemical. 2021 April 1;332. PubMed PMID: 33542590; PubMed Central PMCID: PMC7853653; DOI: 10.1016/j.snb.2021.129447.

Ghaffari R, Yang DS, Kim J, Mansour A, Wright JA Jr, Model JB, Wright DE, Rogers JA, Ray TR. State of Sweat: Emerging Wearable Systems for Real-Time, Noninvasive Sweat Sensing and Analytics. ACS Sens. 2021 Aug 27;6(8):2787-2801. doi: 10.1021/acssensors.1c01133. Epub 2021 Aug 5. PMID: 34351759.

Johnson K, Melchert D, Gianola DS, Begley M, Ray TR. Recent progress in acoustic field-assisted 3D-printing of functional composite materials. MRS Adv. 2021 Sep;6(25):636-643. doi: 10.1557/s43580-021-00090-5. Epub 2021 Jun 22. PMID: 34532078; PMCID: PMC8439201.

Wu CH, Ma H, Balanay R, Ray TR. Skin-interfaced microfluidic systems with spatially-engineered 3D fluidics for sweat capture and analysis. Sci. Adv., in press, doi: 10.1126/sciadv.adg4272.

Wu CH, Ma HJH, Baessler P, Balanay RK, Ray TR. Skin-interfaced microfluidic systems with spatially engineered 3D fluidics for sweat capture and analysis. Sci Adv. 2023 May 3;9(18):eadg4272. doi: 10.1126/sciadv.adg4272. Epub 2023 May 3. PMID: 37134158; PMCID: PMC10881187.

Mehta TI, Arun A, Heiberger C, Cognetti D, Ray TR, Amans MR, Fargen K, Huisman TAGM, Hui F. Venous Pathologies and Interventions of the Head. Semin Neurol. 2023 Jun;43(3):439-453. doi: 10.1055/s-0043-1771512. Epub 2023 Aug 10. PMID: 37562454.

Clark KM, Ray TR. Recent Advances in Skin-Interfaced Wearable Sweat Sensors: Opportunities for Equitable Personalized Medicine and Global Health Diagnostics. ACS Sens. 2023 Oct 27;8(10):3606-3622. doi: 10.1021/acssensors.3c01512. Epub 2023 Sep 25. PMID: 37747817.

Ray TR, Kellogg RT, Fargen KM, Hui F, Vargas J. The perils and promises of generative artificial intelligence in neurointerventional surgery. J Neurointerv Surg. 2023 Dec 19;16(1):4-7. doi: 10.1136/jnis-2023-020353. PMID: 37438101.

Jansen C, Speck M, Greineisen WE, Maaetoft-Udsen K, Cordasco E, Shimoda LM, Stokes AJ, Turner H. Transcriptional and Functional Plasticity Induced by Chronic Insulin Exposure in a Mast Cell-Like Basophilic Leukemia Cell Model. Journal of immunobiology. 2017;2(4). PubMed PMID: 29430572; PubMed Central PMCID: PMC5804893.

Alfulaij N, Meiners F, Michalek J, Small-Howard AL, Turner HC, Stokes AJ. Cannabinoids, the Heart of the Matter. Journal of the American Heart Association. 2018 July 13;7(14). PubMed PMID: 30006489; PubMed Central PMCID: PMC6064852; DOI: 10.1161/JAHA.118.009099.

Horton JS, Shiraishi T, Alfulaij N, Small-Howard AL, Turner HC, Kurokawa T, Mori Y, Stokes AJ. “TRPV1 is a component of the atrial natriuretic signaling complex, and using orally delivered antagonists, presents a valid therapeutic target in the longitudinal reversal and treatment of cardiac hypertrophy and heart failure”. Channels (Austin, Tex.). 2019 December;13(1):1-16. PubMed PMID: 30424709; PubMed Central PMCID: PMC6298697; DOI: 10.1080/19336950.2018.1547611.

Jansen C, Tobita C, Umemoto EU, Starkus J, Rysavy NM, Shimoda LMN, Sung C, Stokes AJ, Turner H. Calcium-dependent, non-apoptotic, large plasma membrane bleb formation in physiologically stimulated mast cells and basophils. Journal of extracellular vesicles. 2019 February 20;8(1):1578589. PubMed PMID: 30815238; PubMed Central PMCID: PMC6383620; DOI: 10.1080/20013078.2019.1578589.

Aldan JT, Jansen C, Speck M, Maaetoft-Udsen K, Cordasco EA, Faiai M, Shimoda LMN, Greineisen WE, Turner H, Stokes AJ. Insulin-induced lipid body accumulation is accompanied by lipid remodelling in model mast cells. Adipocyte. 2019 December;8(1):265-279. PubMed PMID: 31311389; PubMed Central PMCID: PMC6768188; DOI: 10.1080/21623945.2019.1636624.

Jansen C, Shimoda LMN, Starkus J, Lange I, Rysavy N, Maaetoft-Udsen K, Tobita C, Stokes AJ, Turner H. In vitro exposure to Hymenoptera venom and constituents activates discrete ionotropic pathways in mast cells. Channels (Austin, Tex.). 2019 December;13(1):264-286. PubMed PMID: 31237176; DOI: 10.1080/19336950.2019.1629225.

Jansen C, Shimoda LMN, Kawakami JK, Ang L, Bacani AJ, Baker JD, Badowski C, Speck M, Stokes AJ, Small-Howard AL, Turner H. Myrcene and terpene regulation of TRPV1. Channels (Austin, Tex.). 2019 December;13(1):344-366. PubMed PMID: 31446830; PubMed Central PMCID: PMC6768052; DOI: 10.1080/19336950.2019.1654347.

Starkus J, Jansen C, Shimoda LMN, Stokes AJ, Small-Howard AL, Turner H. Diverse TRPV1 responses to cannabinoids. Channels (Austin, Tex.). 2019 December;13(1):172- 191. PubMed PMID: 31096838; PubMed Central PMCID: PMC6557596; DOI: 10.1080/19336950.2019.1619436.

Uchiyama M, Nakao A, Kurita Y, Fukushi I, Takeda K, Numata T, Tran HN, Sawamura S, Ebert M, Kurokawa T, Sakaguchi R, Stokes AJ, Takahashi N, Okada Y, Mori Y. O2-Dependent Protein Internalization Underlies Astrocytic Sensing of Acute Hypoxia by Restricting Multimodal TRPA1 Channel Responses. Curr Biol. 2020 Sep 7;30(17):3378-3396.e7. doi: 10.1016/j.cub.2020.06.047. Epub 2020 Jul 16. PMID: 32679097.

Reimann-Philipp U, Speck M, Orser C, Johnson S, Hilyard A, Turner H, Stokes AJ, Small-Howard AL. Cannabis Chemovar Nomenclature Misrepresents Chemical and Genetic Diversity; Survey of Variations in Chemical Profiles and Genetic Markers in Nevada Medical Cannabis Samples. Cannabis Cannabinoid Res. 2020 Sep 2;5(3):215-230. doi: 10.1089/can.2018.0063. PMID: 32923659; PMCID: PMC7480732.

Jansen C, Baker JD, Kodaira E, Ang L, Bacani AJ, Aldan JT, Shimoda LMN, Salameh M, Small-Howard AL, Stokes AJ, Turner H, Adra CN. Medicine in motion: Opportunities, challenges and data analytics-based solutions for traditional medicine integration into western medical practice. J Ethnopharmacol. 2021 Mar 1;267:113477. doi: 10.1016/j.jep.2020.113477. Epub 2020 Oct 21. PMID: 33098971; PMCID: PMC7577282.

Morash MG, Nixon J, Shimoda LMN, Turner H, Stokes AJ, Small-Howard AL, Ellis LD. Identification of minimum essential therapeutic mixtures from cannabis plant extracts by screening in cell and animal models of Parkinson’s disease. Front Pharmacol. 2022 Oct 5;13:907579. doi: 10.3389/fphar.2022.907579. PMID: 36278152; PMCID: PMC9586206.

Taylor BS, So-Armah K, Tate JP, Marconi VC, Koethe JR, Bedimo RJ, Butt AA, Gibert CL, Goetz MB, Rodriguez-Barradas MC, Womack JA, Gerschenson M, Lo Re V 3rd, Rimland D, Yin MT, Leaf D, Tracy RP, Justice AC, Freiberg MS. HIV and Obesity Comorbidity Increase Interleukin 6 but Not Soluble CD14 or D-Dimer. Journal of acquired immune deficiency syndromes (1999). 2017 August 15;75(5):500-508. PubMed PMID: 28696344; PubMed Central PMCID: PMC5513170.

Kocher M, McDermott M, Lindsey R, Shikuma CM, Gerschenson M, Chow DC, Kohorn LB, Hetzler RK, Kimura IF. Short Communication: HIV Patient Systemic Mitochondrial Respiration Improves with Exercise. AIDS research and human retroviruses. 2017 October;33(10):1035-1037. PubMed PMID: 28467726; PubMed Central PMCID: PMC5650718.

Berry M, Chen J, Hixon A, Gerschenson M, James N, Jameson D, Lew HL, Lozanoff S, Nichols R, Seifried S, Teshima D, Masaki K, Tam E, Ward B, Ward S. Medical School Hotline: School of Medicine Departments – Year in Review 2017, Part 1. Hawaii Journal of Medicine and Public Health: a journal of Asia Pacific Medicine and Public Health. 2018 January;77(1):14-16. PubMed PMID: 29333336; PubMed Central PMCID: PMC5760310.

Panee J, Gerschenson M, Chang L. Associations Between Microbiota, Mitochondrial Function, and Cognition in Chronic Marijuana Users. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. 2018 March;13(1):113-122. PubMed PMID: 29101632; PubMed Central PMCID: PMC5790619.

Geffner ME, Patel K, Jacobson DL, Wu J, Miller TL, Hazra R, Gerschenson M, Sharma T, Silio M, Jao J, Takemoto JK, Van Dyke RB, DiMeglio LA. Changes in insulin sensitivity over time and associated factors in HIV-infected adolescents. AIDS (London, England). 2018 March 13;32(5):613-622. PubMed PMID: 29280758; PubMed Central PMCID: PMC5832600.

Hulgan T, Ramsey BS, Koethe JR, Samuels DC, Gerschenson M, Libutti DE, Sax PE, Daar ES, McComsey GA, Brown TT. Relationships Between Adipose Mitochondrial Function, Serum Adiponectin, and Insulin Resistance in Persons With HIV After 96 Weeks of Antiretroviral Therapy. Journal of acquired immune deficiency syndromes (1999). 2019 March 1;80(3):358-366. PubMed PMID: 30531304; PubMed Central PMCID: PMC6375746; DOI: 10.1097/QAI.0000000000001926.

Gojanovich GS, Shikuma CM, Milne C, Libutti DE, Chow DC, Gerschenson M. Subcutaneous Adipocyte Adenosine Triphosphate Levels in HIV Infected Patients. AIDS research and human retroviruses. 2020 January;36(1):75-82. PubMed PMID: 31407586; PubMed Central PMCID: PMC6944137; DOI: 10.1089/AID.2019.0121.

Kallianpur KJ, Walker M, Gerschenson M, Shikuma CM, Gangcuangco LMA, Kohorn L, Libutti DE, Nir TM, Jahanshad N, Thompson PM, Paul R. Systemic Mitochondrial Oxidative Phosphorylation Protein Levels Correlate with Neuroimaging Measures in Chronically HIV-Infected Individuals. AIDS research and human retroviruses. 2020 January;36(1):83-91. PubMed PMID: 31617381; PubMed Central PMCID: PMC6944134; DOI: 10.1089/AID.2019.0240.

Shikuma CM, Chew GM, Kohorn L, Souza SA, Chow D, SahBandar IN, Park EY, Hanks N, Gangcuangco LMA, Gerschenson M, Ndhlovu LC. Short Communication: Metformin Reduces CD4 T Cell Exhaustion in HIV-Infected Adults on Suppressive Antiretroviral Therapy. AIDS research and human retroviruses. 2020 April;36(4):303-305. PubMed PMID: 31731885; PubMed Central PMCID: PMC7185314; DOI: 10.1089/AID.2019.0078.

Gangcuangco LMA, Mitchell BI, Siriwardhana C, Kohorn LB, Chew GM, Bowler S, Kallianpur KJ, Chow DC, Ndhlovu LC, Gerschenson M, Shikuma CM. Mitochondrial oxidative phosphorylation in peripheral blood mononuclear cells is decreased in chronic HIV and correlates with immune dysregulation. PLoS One. 2020 Apr 30;15(4):e0231761. doi: 10.1371/journal.pone.0231761. Erratum in: PLoS One. 2021 Mar 25;16(3):e0249428. PMID: 32353005; PMCID: PMC7192478.

Gojanovich GS, Jacobson DL, Jao J, Russell JS, Van Dyke RB, Libutti DE, Sharma TS, Geffner ME, Gerschenson M. Mitochondrial Dysfunction and Insulin Resistance in Pubertal Youth Living with Perinatally Acquired HIV. AIDS research and human retroviruses. 2020 September;36(9):703-711. PubMed PMID: 32586116; PubMed Central PMCID: PMC7482121; DOI: 10.1089/AID.2020.0067.

Chew GM, Padua AJP, Chow DC, Souza SA, Clements DM, Corley MJ, Pang APS, Alejandria MM, Gerschenson M, Shikuma CM, Ndhlovu LC. Effects of Brief Adjunctive Metformin Therapy in Virologically Suppressed HIV-Infected Adults on Polyfunctional HIV-Specific CD8 T Cell Responses to PD-L1 Blockade. AIDS research and human retroviruses. 2021 January;37(1):24-33. PubMed PMID: 33019813; PubMed Central PMCID: PMC7864091; DOI: 10.1089/AID.2020.0172.

Jao J, Jacobson DL, Russell JS, Wang J, Yu W, Gojanovich GS, Siminski S, Hyzy L, Geffner ME, Gerschenson M; Pediatric HIV/AIDS Cohort Study. Perinatally acquired HIV infection is associated with abnormal blood mitochondrial function during childhood/adolescence. AIDS. 2021 Jul 15;35(9):1385-1394. doi: 10.1097/QAD.0000000000002884. PMID: 33730749; PMCID: PMC8243810.

Ma C, Hoffmann FW, Marciel MP, Page KE, Williams-Aduja MA, Akana ENL, Gojanovich GS, Gerschenson M, Urschitz J, Moisyadi S, Khadka VS, Rozovsky S, Deng Y, Horgen FD, Hoffmann PR. Upregulated ethanolamine phospholipid synthesis via selenoprotein I is required for effective metabolic reprogramming during T cell activation. Molecular metabolism. 2021 May;47:101170. PubMed PMID: 33484950; PubMed Central PMCID: PMC7881273; DOI: 10.1016/j.molmet.2021.101170.

Mmasa KN, Powis K, Sun S, Makhema J, Mmalane M, Kgole S, Masasa G, Moyo S, Gerschenson M, Mohammed T, Legbedze J, Abrams EJ, Kurland IJ, Geffner ME, Jao J. Gestational diabetes in women living with HIV in Botswana: lower rates with dolutegravir- than with efavirenz-based antiretroviral therapy. HIV Med. 2021 May 18;. doi: 10.1111/hiv.13120. [Epub ahead of print] PubMed PMID: 34003565.

Gojanovich GS, Jacobson DL, Broadwell C, Karalius B, Kirmse B, Geffner ME, Jao J, Van Dyke RB, McFarland EJ, Silio M, Crain M, Gerschenson M; Pediatric HIV/AIDS Cohort Study. Associations of FGF21 and GDF15 with mitochondrial dysfunction in children living with perinatally-acquired HIV: A cross-sectional evaluation of pediatric AIDS clinical trials group 219/219C. PLoS One. 2021 Dec 31;16(12):e0261563. doi: 10.1371/journal.pone.0261563. PMID: 34972147; PMCID: PMC8719680.

Jao J, Sun S, Bonner LB, Legbedze J, Mmasa KN, Makhema J, Mmalane M, Kgole S, Masasa G, Moyo S, Gerschenson M, Mohammed T, Abrams EJ, Kurland IJ, Geffner ME, Powis KM. Lower Insulin Sensitivity in Newborns with In Utero HIV and Antiretroviral Exposure Who Are Uninfected in Botswana. J Infect Dis. 2022 Nov 28;226(11):2002-2009. doi: 10.1093/infdis/jiac416. PMID: 36240387.

Ma C, Hoffmann FW, Nunes LG, Urena F, Andrukhiv A, Gerschenson M, Pitts MW, Hoffmann PR. Selenoprotein I deficiency in T cells promotes differentiation into tolerant phenotypes while decreasing Th17 pathology. J Leukoc Biol. 2022 Dec;112(6):1387-1397. doi: 10.1002/JLB.1A0122-080R. Epub 2022 Aug 2. PMID: 35916034; PMCID: PMC9701159.

Maison DP, Deng Y, Gerschenson M. SARS-CoV-2 and the host-immune response. Front Immunol. 2023 Jun 19;14:1195871. doi: 10.3389/fimmu.2023.1195871. PMID: 37404823; PMCID: PMC10315470.

Kaur H, Minchella P, Alvarez-Carbonell D, Purandare N, Nagampalli VK, Blankenberg D, Hulgan T, Gerschenson M, Karn J, Aras S, Kallianpur AR. Contemporary Antiretroviral Therapy Dysregulates Iron Transport and Augments Mitochondrial Dysfunction in HIV-Infected Human Microglia and Neural-Lineage Cells. Int J Mol Sci. 2023 Jul 31;24(15):12242. doi: 10.3390/ijms241512242. PMID: 37569616; PMCID: PMC10419149.

Dirajlal-Fargo S, Maison DP, Durieux JC, Andrukhiv A, Funderburg N, Ailstock K, Gerschenson M, Mccomsey GA. Altered mitochondrial respiration in peripheral blood mononuclear cells of post-acute sequelae of SARS-CoV-2 infection. Mitochondrion. 2024 Feb 9;75:101849. doi: 10.1016/j.mito.2024.101849. Epub ahead of print. PMID: 38341012.

Favre G, Laurain A, Aranyi T, Szeri F, Fulop K, Le Saux O, Duranton C, Kauffenstein G, Martin L, Lefthériotis G. The ABCC6 Transporter: A New Player in Biomineralization. International journal of molecular sciences. 2017 September 11;18(9). PubMed PMID: 28891970; PubMed Central PMCID: PMC5618590.

Dedinszki D, Szeri F, Kozák E, Pomozi V, Tőkési N, Mezei TR, Merczel K, Letavernier E, Tang E, Le Saux O, Arányi T, van de Wetering K, Váradi A. Oral administration of pyrophosphate inhibits connective tissue calcification. EMBO molecular medicine. 2017 November;9(11):1463-1470. PubMed PMID: 28701330; PubMed Central PMCID: PMC5666306.

Bauer C, Le Saux O, Pomozi V, Aherrahrou R, Kriesen R, Stölting S, Liebers A, Kessler T, Schunkert H, Erdmann J, Aherrahrou Z. Etidronate prevents dystrophic cardiac calcification by inhibiting macrophage aggregation. Scientific reports. 2018 April 11;8(1):5812. PubMed PMID: 29643466; PubMed Central PMCID: PMC5895639.

Kauffenstein G, Yegutkin GG, Khiati S, Pomozi V, Le Saux O, Leftheriotis G, Lenaers G, Henrion D, Martin L. Alteration of Extracellular Nucleotide Metabolism in Pseudoxanthoma Elasticum. The Journal of investigative dermatology. 2018 August;138(8):1862-1870. PubMed PMID: 29501384; DOI: 10.1016/j.jid.2018.02.023.

Letavernier E, Kauffenstein G, Huguet L, Navasiolava N, Bouderlique E, Tang E, Delaitre L, Bazin D, de Frutos M, Gay C, Perez J, Verpont MC, Haymann JP, Pomozi V, Zoll J, Le Saux O, Daudon M, Leftheriotis G, Martin L. ABCC6 Deficiency Promotes Development of Randall Plaque. Journal of the American Society of Nephrology : JASN. 2018 September;29(9):2337-2347. PubMed PMID: 29991491; PubMed Central PMCID: PMC6115671; DOI: 10.1681/ASN.2017101148.

De Vilder EYG, Cardoen S, Hosen MJ, Le Saux O, De Zaeytijd J, Leroy BP, De Reuck J, Coucke PJ, De Paepe A, Hemelsoet D, Vanakker OM. Pathogenic variants in the ABCC6 gene are associated with an increased risk for ischemic stroke. Brain pathology (Zurich, Switzerland). 2018 November;28(6):822-831. PubMed PMID: 29722917; DOI: 10.1111/bpa.12620.

Pomozi V, Julian CB, Zoll J, Pham K, Kuo S, Tőkési N, Martin L, Váradi A, Le Saux O. Dietary Pyrophosphate Modulates Calcification in a Mouse Model of Pseudoxanthoma Elasticum: Implication for Treatment of Patients. The Journal of investigative dermatology. 2019 May;139(5):1082-1088. PubMed PMID: 30468740; PubMed Central PMCID: PMC6478508; DOI: 10.1016/j.jid.2018.10.040.

Panee J, Pomozi V, Franke AA, Le Saux O, Gerschenson M. Chronic marijuana use moderates the correlations of serum cholesterol with systemic mitochondrial function and fluid cognition. Mitochondrion. 2020 May;52:135-143. PubMed PMID: 32169611; PubMed Central PMCID: PMC8041574; DOI: 10.1016/j.mito.2020.03.006.

Brampton C, Pomozi V, Chen LH, Apana A, McCurdy S, Zoll J, Boisvert WA, Lambert G, Henrion D, Blanchard S, Kuo S, Leftheriotis G, Martin L, Le Saux O. ABCC6 deficiency promotes dyslipidemia and atherosclerosis. Scientific reports. 2021 February 16;11(1):3881. PubMed PMID: 33594095; PubMed Central PMCID: PMC7887252; DOI: 10.1038/s41598-021-82966-y.

Shimada BK, Pomozi V, Zoll J, Kuo S, Martin L, Le Saux O. ABCC6, Pyrophosphate and Ectopic Calcification: Therapeutic Solutions. International journal of molecular sciences. 2021 April 27;22(9). PubMed PMID: 33925341; PubMed Central PMCID: PMC8123679; DOI: 10.3390/ijms22094555.

Leftheriotis G, Navasiolava N, Clotaire L, Duranton C, Le Saux O, Bendahhou S, Laurain A, Rubera I, Martin L. Relationships between Plasma Pyrophosphate, Vascular Calcification and Clinical Severity in Patients Affected by Pseudoxanthoma Elasticum. J Clin Med. 2022 May 5;11(9):2588. doi: 10.3390/jcm11092588. PMID: 35566717; PMCID: PMC9100273.

Roberts FL, Rashdan NA, Phadwal K, Markby GR, Dillon S, Zoll J, Berger J, Milne E, Orriss IR, Karsenty G, Le Saux O, Morton NM, Farquharson C, MacRae VE. Osteoblast-specific deficiency of ectonucleotide pyrophosphatase or phosphodiesterase-1 engenders insulin resistance in high-fat diet fed mice. J Cell Physiol. 2021 Jun;236(6):4614-4624. doi: 10.1002/jcp.30194. Epub 2020 Dec 10. PMID: 33305372; PMCID: PMC9665351.

Kauffenstein G, Martin L, Le Saux O. The Purinergic Nature of Pseudoxanthoma Elasticum. Biology (Basel). 2024 Jan 26;13(2):74. doi: 10.3390/biology13020074. PMID: 38392293; PMCID: PMC10886499.

Brampton C, Pomozi V, Le Corre Y, Zoll J, Kauffenstein G, Ma C, Hoffmann PR, Martin L, Le Saux O. Bone Marrow-Derived ABCC6 Is an Essential Regulator of Ectopic Calcification In PXE. J Invest Dermatol. 2024 Feb 15:S0022-202X(24)00110-6. doi: 10.1016/j.jid.2024.01.026. Epub ahead of print. PMID: 38367909.

Laurain A, Rubera I, Razzouk-Cadet M, Bonnafous S, Albuquerque M, Paradis V, Patouraux S, Duranton C, LeSaux O, Lefthériotis G, Tran A, Anty R, Gual P, Iannelli A, Favre G. Arterial Calcifications in Patients with Liver Cirrhosis Are Linked to Hepatic Deficiency of Pyrophosphate Production Restored by Liver Transplantation. Biomedicines. 2022 Jun 24;10(7):1496. doi: 10.3390/biomedicines10071496. PMID: 35884801; PMCID: PMC9312703.

Baba Y, Higa JK, Shimada BK, Horiuchi KM, Suhara T, Kobayashi M, Woo JD, Aoyagi H, Marh KS, Kitaoka H, Matsui T. Protective effects of the mechanistic target of rapamycin against excess iron and ferroptosis in cardiomyocytes. American journal of physiology. Heart and circulatory physiology. 2018 March 1;314(3):H659-H668. PubMed PMID: 29127238; PubMed Central PMCID: PMC5899260.

Kobayashi M, Suhara T, Baba Y, Kawasaki NK, Higa JK, Matsui T. Pathological Roles of Iron in Cardiovascular Disease. Current drug targets. 2018;19(9):1068-1076. PubMed PMID: 29874997; PubMed Central PMCID: PMC6469984; DOI: 10.2174/1389450119666180605112235.

Kobayashi M, Higa JK, Matsui T. The role of ubiquitin in cardiac ischemia-reperfusion injury. American journal of physiology. Heart and circulatory physiology. 2019 March 1;316(3):H583-H585. PubMed PMID: 30657725; PubMed Central PMCID: PMC6459312; DOI: 10.1152/ajpheart.00018.2019.

Yorichika N, Baba Y, Shimada BK, Thakore M, Wong SM, Kobayashi M, Higa JK, Matsui T. The effects of Tel2 on cardiomyocyte survival. Life sciences. 2019 September 1;232:116665. PubMed PMID: 31323273; PubMed Central PMCID: PMC6698408; DOI: 10.1016/j.lfs.2019.116665.

Mishra PK, Adameova A, Hill JA, Baines CP, Kang PM, Downey JM, Narula J, Takahashi M, Abbate A, Piristine HC, Kar S, Su S, Higa JK, Kawasaki NK, Matsui T. Guidelines for evaluating myocardial cell death. American journal of physiology. Heart and circulatory physiology. 2019 November 1;317(5):H891-H922. PubMed PMID: 31418596; PubMed Central PMCID: PMC6879915; DOI: 10.1152/ajpheart.00259.2019.

Komai K, Kawasaki NK, Higa JK, Matsui T. The Role of Ferroptosis in Adverse Left Ventricular Remodeling Following Acute Myocardial Infarction. Cells. 2022 Apr 20;11(9):1399. doi: 10.3390/cells11091399. PMID: 35563704; PMCID: PMC9102292.

Shimada BK, Yorichika N, Higa JK, Baba Y, Kobayashi M, Aoyagi T, Suhara T, Matsui T. mTOR-mediated calcium transients affect cardiac function in ex vivo ischemia-reperfusion injury. Physiol Rep. 2021 Mar;9(6):e14807. doi: 10.14814/phy2.14807. PMID: 33769701; PMCID: PMC7995667.

Yang X, Kawasaki NK, Min J, Matsui T, Wang F. Ferroptosis in heart failure. J Mol Cell Cardiol. 2022 Oct 20;173:141-153. doi: 10.1016/j.yjmcc.2022.10.004. Epub ahead of print. PMID: 36273661.

Kawasaki NK, Suhara T, Komai K, Shimada BK, Yorichika N, Kobayashi M, Baba Y, Higa JK, Matsui T. The role of ferroptosis in cell-to-cell propagation of cell death initiated from focal injury in cardiomyocytes. Life Sci. 2023 Nov 1;332:122113. doi: 10.1016/j.lfs.2023.122113. Epub 2023 Sep 20. PMID: 37739163; PMCID: PMC10591893.

Doi ML, Tatsuno SY, Singh G, Tatsuno EM, Mau MM. Neurological Complications in a Polynesian Traveler with Dengue. Hawaii Journal of Medicine and Public Health: a journal of Asia Pacific Medicine and Public Health. 2017 October;76(10):275-278. PubMed PMID: 29018589; PubMed Central PMCID: PMC5630466.

Deguchi M, Mau MKLM, Davis J, Niederman R. Preventable Tooth Loss in Hawaii: The Role of Socioeconomic Status, Diabetes, and Dental Visits. Preventing chronic disease. 2017 November 16;14:E115. PubMed PMID: 29144892; PubMed Central PMCID: PMC5695642.

Chang SP, Chun M, Guerrero A, Harris C, Kaholokula JK, Mau ML, Nakamura K, Thompson K, Zalud I. Medical School Hotline: School of Medicine Departments – Year in Review 2017, Part 2. Hawaii Journal of Medicine and Public Health: a journal of Asia Pacific Medicine and Public Health. 2018 February;77(2):35-37. PubMed PMID: 29435389; PubMed Central PMCID: PMC5801527.

Deguchi M, Wey A, Mau M, Gandhi K, Davis J. Increasing dental health-care utilisation for all: understanding individual factors and place factors in Hawaii. International dental journal. 2019 March 12. PubMed PMID: 30861109; DOI: 10.1111/idj.12477.

Mau MKLM, Minami CM, Stotz SA, Albright CL, Kana’iaupuni SM, Guth HK. Qualitative study on voyaging and health: perspectives and insights from the medical officers during the Worldwide Voyage. BMJ Open. 2021 Jul 7;11(7):e048767. doi: 10.1136/bmjopen-2021-048767. PMID: 34233995; PMCID: PMC8264866.

Lee CG, Heckman-Stoddard B, Dabelea D, Gadde KM, Ehrmann D, Ford L, Prorok P, Boyko EJ, Pi-Sunyer X, Wallia A, Knowler WC, Crandall JP, Temprosa M; Diabetes Prevention Program Research Group; Diabetes Prevention Program Research Group:. Effect of Metformin and Lifestyle Interventions on Mortality in the Diabetes Prevention Program and Diabetes Prevention Program Outcomes Study. Diabetes Care. 2021 Dec;44(12):2775-2782. doi: 10.2337/dc21-1046. Epub 2021 Oct 25. PMID: 34697033; PMCID: PMC8669534.

Gottlieb K, Lindquist C, Mala TA, Mau MKLM. Reflections on Dr. Donald A.B. Lindberg and Native Voices. Stud Health Technol Inform. 2022 Feb 1;288:362-371. doi: 10.3233/SHTI211009. PMID: 35102854.

Kawamura MY, Mau MK, Soon R, Yamasato K. A Scoping Review on Gestational Diabetes in Hawai’i: A “Window of Opportunity” to Address Intergenerational Risk for Type 2 Diabetes Mellitus. Hawaii J Health Soc Welf. 2022 Mar;81(3):58-70. PMID: 35261986; PMCID: PMC8899083.

Kanaya AM, Hsing AW, Panapasa SV, Kandula NR, Araneta MRG, Shimbo D, Wang P, Gomez SL, Lee J, Narayan KMV, Mau MKLM, Bose S, Daviglus ML, Hu FB, Islam N, Jackson CL, Kataoka-Yahiro M, Kauwe JSK, Liu S, Ma GX, Nguyen T, Palaniappan L, Setiawan VW, Trinh-Shevrin C, Tsoh JY, Vaidya D, Vickrey B, Wang TJ, Wong ND, Coady S, Hong Y. Knowledge Gaps, Challenges, and Opportunities in Health and Prevention Research for Asian Americans, Native Hawaiians, and Pacific Islanders: A Report From the 2021 National Institutes of Health Workshop. Ann Intern Med. 2022 Apr;175(4):574-589. doi: 10.7326/M21-3729. Epub 2022 Jan 4. PMID: 34978851; PMCID: PMC9018596.

Gottlieb K, Lindquist C, Mala TA, Mau MKLM. Reflections on Dr. Donald A.B. Lindberg and Native Voices. Inf Serv Use. 2022 Apr 26;41(3-4):315-323. doi: 10.3233/ISU-210131. PMID: 35602566; PMCID: PMC9074425.

Dye CK, Corley MJ, Ing C, Lum-Jones A, Li D, Mau MKLM, Maunakea AK. Shifts in the immunoepigenomic landscape of monocytes in response to a diabetes-specific social support intervention: a pilot study among Native Hawaiian adults with diabetes. Clin Epigenetics. 2022 Jul 18;14(1):91. doi: 10.1186/s13148-022-01307-6. PMID: 35851422; PMCID: PMC9295496.

White NH, Pan Q, Knowler WC, Schroeder EB, Dabelea D, Chew EY, Blodi B, Goldberg RB, Pi-Sunyer X, Darwin C, Schlögl M, Nathan DM; Diabetes Prevention Program Outcome Study (DPPOS) Research Group. Risk Factors for the Development of Retinopathy in Prediabetes and Type 2 Diabetes: The Diabetes Prevention Program Experience. Diabetes Care. 2022 Aug 30:dc220860. doi: 10.2337/dc22-0860. Epub ahead of print. PMID: 36098658.

Shams-White MM, Tjaden AH, Edelstein SL, Bassiouni S, Kahle LL, Kim C, Pi-Sunyer X, Temple KA, Venditti EM, Reedy J, Heckman-Stoddard BM; DPP Research Group. The 2018 World Cancer Research Fund (WCRF)/American Institute for Cancer Research (AICR) score and diabetes risk in the Diabetes Prevention Program Outcomes Study (DPPOS). BMC Nutr. 2022 Sep 21;8(1):105. doi: 10.1186/s40795-022-00596-7. PMID: 36131333; PMCID: PMC9494851.

Mau MKLM, Baumhofer Merritt NK, Werner K, Oneha MFO. Engaging Community Health Centers to understand their perceptions and interest in longitudinal cohort research on diabetes mellitus in Native Hawaiian communities: Initial insights from the Waimānalo community. Front Public Health. 2022 Dec 8;10:1035600. doi: 10.3389/fpubh.2022.1035600. PMID: 36568795; PMCID: PMC9780047.

Domalpally A, Whittier SA, Pan Q, Dabelea DM, Darwin CH, Knowler WC, Lee CG, Luchsinger JA, White NH, Chew EY; Diabetes Prevention Program Research (DPPOS) Group. Association of Metformin With the Development of Age-Related Macular Degeneration. JAMA Ophthalmol. 2022 Dec 22. doi: 10.1001/jamaophthalmol.2022.5567. Epub ahead of print. PMID: 36547967.

Stotz SA, Moore KR, Charron-Prochownik D, Fischl A, Spencer K, Mau MKLM. A Qualitative Study on Preventing Gestational Diabetes in Native Hawaiian and Pacific Islander Adolescent Females: Perspectives from an Expert Panel of Health Care Providers. Hawaii J Health Soc Welf. 2023 Jan;82(1):10-15. PMID: 36685779; PMCID: PMC9850826.

Li JH, Brenner LN, Kaur V, Figueroa K, Schroeder P, Huerta-Chagoya A; MAGIC Investigators; Diabetes Prevention Program (DPP) Research Group; Udler MS, Leong A, Mercader JM, Florez JC. Genome-wide association analysis identifies ancestry-specific genetic variation associated with acute response to metformin and glipizide in SUGAR-MGH. Diabetologia. 2023 Jul;66(7):1260-1272. doi: 10.1007/s00125-023-05922-7. Epub 2023 May 26. PMID: 37233759.

Li JH, Perry JA, Jablonski KA, Srinivasan S, Chen L, Todd JN, Harden M, Mercader JM, Pan Q, Dawed AY, Yee SW, Pearson ER, Giacomini KM, Giri A, Hung AM, Xiao S, Williams LK, Franks PW, Hanson RL, Kahn SE, Knowler WC, Pollin TI, Florez JC; Diabetes Prevention Program Research Group:. Identification of Genetic Variation Influencing Metformin Response in a Multiancestry Genome-Wide Association Study in the Diabetes Prevention Program (DPP). Diabetes. 2023 Aug 1;72(8):1161-1172. doi: 10.2337/db22-0702. PMID: 36525397; PMCID: PMC10382652.

Chung-Do JJ, Scott SK, Jones BR, Look MA, Taira DA, Palafox NA, Farrar K, Mau MKLM. "Community 101 for researchers": an online training program to build capacity for ethical community-engaged research with Native Hawaiians and Pacific Islanders. Front Public Health. 2024 Jan 5;11:1121748. doi: 10.3389/fpubh.2023.1121748. PMID: 38249373; PMCID: PMC10796991.

Mau MKLM, Stotz SA, Minami CM, Kane HH, Crabbe KM, Guth HK. Exploring perspectives and insights of experienced voyagers on human health and Polynesian oceanic voyaging: A qualitative study. PLoS One. 2024 Apr 15;19(4):e0296820. doi: 10.1371/journal.pone.0296820. PMID: 38620018; PMCID: PMC11018278.

Lee CG, Ciarleglio A, Edelstein SL, Crandall JP, Dabelea D, Goldberg RB, Kahn SE, Knowler WC, Ma MT, White NH, Herman WH; Diabetes Prevention Program Research Group. Prevalence of Distal Symmetrical Polyneuropathy by Diabetes Prevention Program Treatment Group, Diabetes Status, Duration of Diabetes, and Cumulative Glycemic Exposure. Diabetes Care. 2024 May 1;47(5):810-817. doi: 10.2337/dc23-2009. PMID: 38502874; PMCID: PMC11043227.

Roman MJ, Pugh NL, Devereux RB, Eagle KA, Holmes K, LeMaire SA, Milewski RK, Morris SA, Prakash SK, Pyeritz RE, Ravekes WJ, Shohet RV, Song HK, Asch FM. Aortic Dilatation Associated With Bicuspid Aortic Valve: Relation to Sex, Hemodynamics, and Valve Morphology (the National Heart Lung and Blood Institute-Sponsored National Registry of Genetically Triggered Thoracic Aortic Aneurysms and Cardiovascular Conditions). The American journal of cardiology. 2017 October 1;120(7):1171-1175. PubMed PMID: 28802510; PubMed Central PMCID: PMC5593782.

Krepp JM, Roman MJ, Devereux RB, Bruce A, Prakash SK, Morris SA, Milewicz DM, Holmes KW, Ravekes W, Shohet RV, Pyeritz RE, Maslen CL, Kroner BL, Eagle KA, Preiss L, Asch FM. Bicuspid and unicuspid aortic valves: Different phenotypes of the same disease? Insight from the GenTAC Registry. Congenital heart disease. 2017 December;12(6):740-745. PubMed PMID: 28805011; PubMed Central PMCID: PMC5819742.

Akram KM, Moyo NA, Leeming GH, Bingle L, Jasim S, Hussain S, Schorlemmer A, Kipar A, Digard P, Tripp RA, Shohet RV, Bingle CD, Stewart JP. An innate defense peptide BPIFA1/SPLUNC1 restricts influenza A virus infection. Mucosal immunology. 2018 January;11(1):71-81. PubMed PMID: 28513596; DOI: 10.1038/mi.2017.45.

Bratincsak A, Limm-Chan BN, Nerurkar VR, Ching LL, Reddy VD, Lim E, Shohet RV, Melish ME. Study design and rationale to assess Doxycycline Efficacy in preventing coronary Artery Lesions in children with Kawasaki disease (DEAL trial) – A phase II clinical trial. Contemporary clinical trials. 2018 February;65:33-38. PubMed PMID: 29313803; PubMed Central PMCID: PMC5803379.

Williams AL, Khadka V, Tang M, Avelar A, Schunke KJ, Menor M, Shohet RV. HIF1 mediates a switch in pyruvate kinase isoforms after myocardial infarction. Physiological genomics. 2018 July 1;50(7):479-494. PubMed PMID: 29652636; PubMed Central PMCID: PMC6087881; DOI: 10.1152/physiolgenomics.00130.2017.

Schunke KJ, Walton CB, Veal DR, Mafnas CT, Anderson CD, Williams AL, Shohet RV. Protein Kinase C Binding Protein 1(PRKCBP1) Inhibits Hypoxia Inducible Factor 1 (HIF-1) in the Heart. Cardiovascular research. 2018 November 5. PubMed PMID: 30395227; DOI: 10.1093/cvr/cvy278.

Marcinko MC, Darrow AL, Tuia AJ, Shohet RV. Sex influences susceptibility to methamphetamine cardiomyopathy in mice. Physiological reports. 2019 March;7(6):e14036. PubMed PMID: 30891941; PubMed Central PMCID: PMC6424857; DOI: 10.14814/phy2.14036.

Williams AL, Walton CB, MacCannell KA, Avelar A, Shohet RV. HIF-1 regulation of miR- 29c impairs SERCA2 expression and cardiac contractility. American journal of physiology. Heart and circulatory physiology. 2019 March 1;316(3):H554-H565. PubMed PMID: 30575439; PubMed Central PMCID: PMC6459310; DOI: 10.1152/ajpheart.00617.2018.

Lam L, Ahn HJ, Okajima K, Schoenman K, Seto TB, Shohet RV, Miyamura J, Sentell TL, Nakagawa K. Gender Differences in the Rate of 30-Day Readmissions after Percutaneous Coronary Intervention for Acute Coronary Syndrome. Women’s health issues : official publication of the Jacobs Institute of Women’s Health. 2019 January;29(1):17-22. PubMed PMID: 30482594; PubMed Central PMCID: PMC6296765; DOI: 10.1016/j.whi.2018.09.002.

Ching LL, Nerurkar VR, Lim E, Shohet RV, Melish ME, Bratincsak A. Elevated Levels of Pentraxin 3 Correlate With Neutrophilia and Coronary Artery Dilation During Acute Kawasaki Disease. Frontiers in pediatrics. 2020;8:295. PubMed PMID: 32670996; PubMed Central PMCID: PMC7330095; DOI: 10.3389/fped.2020.00295.

Baldassari AR, Sitlani CM, Highland HM, Arking DE, Buyske S, Darbar D, Gondalia R, Graff M, Guo X, Heckbert SR, Hindorff LA, Hodonsky CJ, Ida Chen YD, Kaplan RC, Peters U, Post W, Reiner AP, Rotter JI, Shohet RV, Seyerle AA, Sotoodehnia N, Tao R, Taylor KD, Wojcik GL, Yao J, Kenny EE, Lin HJ, Soliman EZ, Whitsel EA, North KE, Kooperberg C, Avery CL. Multi- Ethnic Genome-Wide Association Study of Decomposed Cardioelectric Phenotypes Illustrates Strategies to Identify and Characterize Evidence of Shared Genetic Effects for Complex Traits. Circulation. Genomic and precision medicine. 2020 August;13(4):e002680. PubMed PMID: 32602732; PubMed Central PMCID: PMC7520945; DOI: 10.1161/CIRCGEN.119.002680.

Williams AL, Khadka VS, Anagaran MCT, Lee K, Avelar A, Deng Y, Shohet RV. miR-125 family regulates XIRP1 and FIH in response to myocardial infarction. Physiological genomics. 2020 August 1;52(8):358-368. PubMed PMID: 32716698; PubMed Central PMCID: PMC7473889; DOI: 10.1152/physiolgenomics.00041.2020.

Williams AL, Walton CB, Pinell B, Khadka VS, Dunn B, Lee K, Anagaran MCT, Avelar A, Shohet RV. Ischemic heart injury leads to HIF1-dependent differential splicing of CaMK2γ. Sci Rep. 2021 Jun 23;11(1):13116. doi: 10.1038/s41598-021-92426-2. PMID: 34162925; PMCID: PMC8222303.

Anderson CD, Walton CB, Shohet RV. A Comparison of Focused and Unfocused Ultrasound for Microbubble-Mediated Gene Delivery. Ultrasound Med Biol. 2021 Jul;47(7):1785-1800. doi: 10.1016/j.ultrasmedbio.2021.02.016. Epub 2021 Mar 31. PMID: 33812691; PMCID: PMC8169610.

Knutson AK, Williams AL, Boisvert WA, Shohet RV. HIF in the heart: development, metabolism, ischemia, and atherosclerosis. J Clin Invest. 2021 Sep 1;131(17):e137557. doi: 10.1172/JCI137557. PMID: 34623330; PMCID: PMC8409592.

Holmes KW, Markwardt S, Eagle KA, Devereux RB, Weinsaft JW, Asch FM, LeMaire SA, Maslen CL, Song HK, Milewicz DM, Prakash SK, Guo D, Morris SA, Pyeritz RE, Milewski RC, Ravekes WJ, Dietz HC, Shohet RV, Silberbach M, Roman MJ; GenTAC Investigators. Cardiovascular Outcomes in Aortopathy: GenTAC Registry of Genetically Triggered Aortic Aneurysms and Related Conditions. J Am Coll Cardiol. 2022 May 31;79(21):2069-2081. doi: 10.1016/j.jacc.2022.03.367. PMID: 35618343; PMCID: PMC8972470.

Cobb MS, Tao S, Shortt K, Girgis M, Hauptman J, Schriewer J, Chin Z, Dorfman E, Campbell K, Heruth DP, Shohet RV, Dawn B, Konorev EA. Smad3 promotes adverse cardiovascular remodeling and dysfunction in doxorubicin-treated hearts. Am J Physiol Heart Circ Physiol. 2022 Dec 1;323(6):H1091-H1107. doi: 10.1152/ajpheart.00312.2022. Epub 2022 Oct 21. PMID: 36269647; PMCID: PMC9678413.

Anderson CD, Arthur JA, Zhang Y, Bharucha N, Karakikes I, Shohet RV. Non-viral in vivo cytidine base editing in hepatocytes using focused ultrasound targeted microbubbles. Mol Ther Nucleic Acids. 2023 Aug 1;33:733-737. doi: 10.1016/j.omtn.2023.07.032. PMID: 37662969; PMCID: PMC10468349.

Stephens SB, Shalhub S, Dodd N, Li J, Huang M, Oda S, Kancherla K, Doan TT, Prakash SK, Weigand JD, Asch FM, Beecroft T, Cecchi A, Shittu T, Preiss L, LeMaire SA, Devereux RB, Pyeritz RE, Holmes KW, Roman MJ, Lacro RV, Shohet RV, Krishnamurthy R, Eagle K, Byers P, Milewicz DM, Morris SA. Vertebral Tortuosity Is Associated With Increased Rate of Cardiovascular Events in Vascular Ehlers-Danlos Syndrome. J Am Heart Assoc. 2023 Oct 3;12(19):e029518. doi: 10.1161/JAHA.123.029518. Epub 2023 Sep 30. PMID: 37776192; PMCID: PMC10727246.

Brown SC, King ZA, Kuohn L, Kamel H, Gilmore EJ, Frontera JA, Murthy S, Kim JA, Omay SB, Falcone GJ, Sheth KN. Association of race and ethnicity to incident epilepsy, or epileptogenesis, after subdural hematoma. Neurology. 2020 November 24;95(21):e2890-e2899. PubMed PMID: 32907969; PubMed Central PMCID: PMC7734738; DOI: 10.1212/WNL.0000000000010742.

Sader E, Abdalkader M, Thom N, Nguyen TN, McDonald S, Greer D, Brown SC, Mohamedali A, Gutierrez J, Shi H, Morris J, Lopez-Rivera V, Sheth SA, Sloane KL, Singhal A, Atchaneeyasakul K, Liebeskind DS, Khandelwal P, Bach I, Raz E, Cervantes-Arslanian AM. Endovascular Treatment of Infective Endocarditis-Related Acute Large Vessel Occlusion Stroke. J Stroke Cerebrovasc Dis. 2021 Jun;30(6):105775. doi: 10.1016/j.jstrokecerebrovasdis.2021.105775. Epub 2021 Apr 8. PMID: 33839380.

Leasure AC, Acosta JN, Both C, Szejko N, Brown SC, Sheth KN, Falcone GJ. Stroke Disparities Among Nonracial Minorities in the All of Us Research Program. Stroke. 2021 Aug;52(8):e488-e490. doi: 10.1161/STROKEAHA.121.034903. Epub 2021 Jun 18. PMID: 34139858; PMCID: PMC8316290.

Ammar AA, Ammar MA, Owusu KA, Brown SC, Kaddouh F, Elsamadicy AA, Acosta JN, Falcone GJ. Andexanet Alfa Versus 4-Factor Prothrombin Complex Concentrate for Reversal of Factor Xa Inhibitors in Intracranial Hemorrhage. Neurocrit Care. 2021 Aug;35(1):255-261. doi: 10.1007/s12028-020-01161-5. Epub 2021 Jan 6. PMID: 33403588.

Brown SC, Cormier J, Tuan J, Lier AJ, McGuone D, Armstrong PM, Kaddouh F, Parikh S, Landry ML, Gobeske KT. Four Human Cases of Eastern Equine Encephalitis in Connecticut, USA, during a Larger Regional Outbreak, 2019. Emerg Infect Dis. 2021 Aug;27(8):2042–51. doi: 10.3201/eid2708.203730. PMID: 34289334; PMCID: PMC8314835.

Acosta JN, Leasure AC, Both CP, Szejko N, Brown S, Torres-Lopez V, Abdelhakim S, Schindler J, Petersen N, Sansing L, Gill TM, Sheth KN, Falcone GJ. Cardiovascular Health Disparities in Racial and Other Underrepresented Groups: Initial Results From the All of Us Research Program. J Am Heart Assoc. 2021 Sep 7;10(17):e021724. doi: 10.1161/JAHA.121.021724. Epub 2021 Aug 25. PMID: 34431358.

Acosta JN, Both CP, Szejko N, Leasure AC, Abdelhakim S, Torres-Lopez VM, Brown SC, Matouk CC, Gunel M, Sheth KN, Falcone GJ. Genetically Determined Low-Density Lipoprotein Cholesterol and Risk of Subarachnoid Hemorrhage. Ann Neurol. 2022 Jan;91(1):145-149. doi: 10.1002/ana.26250. Epub 2021 Nov 1. PMID: 34709661.

Kuohn LR, Herman AL, Soto AL, Brown SC, Gilmore EJ, Hirsch LJ, Matouk CC, Sheth KN, Kim JA. Hospital Revisits for Post-Ischemic Stroke Epilepsy after Acute Stroke Interventions. J Stroke Cerebrovasc Dis. 2022 Jan;31(1):106155. doi: 10.1016/j.jstrokecerebrovasdis.2021.106155. Epub 2021 Oct 21. PMID: 34688213; PMCID: PMC8766898.

Bruno MK, Watanabe G, Gao F, Seto T, Nakagawa K, Trinacty C, Brown S, Taira DA. Difference in rural and urban Medicare prescription pattern for Parkinson’s disease in Hawai’i. Clin Park Relat Disord. 2022 Apr 22;6:100144. doi: 10.1016/j.prdoa.2022.100144. PMID: 35521293; PMCID: PMC9062359.

Ye Y, Noche RB, Szejko N, Both CP, Acosta JN, Leasure AC, Brown SC, Sheth KN, Gill TM, Zhao H, Falcone GJ. A genome-wide association study of frailty identifies significant genetic correlation with neuropsychiatric, cardiovascular, and inflammation pathways. Geroscience. 2023 Mar 16. doi: 10.1007/s11357-023-00771-z. Epub ahead of print. PMID: 36928559.

Choi JW, Ho R, Zhang YJ, Sae-Ow W, Hui FK, Brown SC, Tsappidi S. A rare case of solitary, isolated dural metastasis from hepatocellular carcinoma mimicking a meningioma. Surg Neurol Int. 2023 Nov 10;14:398. doi: 10.25259/SNI_733_2023. PMID: 38053699; PMCID: PMC10695471.

Kulkarni M, Vishwakarma B, Sen S, Anupuram S, Date AA. Development and evaluation of taste masked dry syrup formulation of potassium chloride. AAPS open. 2019;5(1):1. PubMed PMID: 30957011; PubMed Central PMCID: PMC6421559; DOI: 10.1186/s41120-019-0030-z.

Hoang T, Zierden H, Date A, Ortiz J, Gumber S, Anders N, He P, Segars J, Hanes J, Mahendroo M, Ensign LM. Development of a mucoinert progesterone nanosuspension for safer and more effective prevention of preterm birth. Journal of controlled release : official journal of the Controlled Release Society. 2019 February 10;295:74-86. PubMed PMID: 30597245; PubMed Central PMCID: PMC6398330; DOI: 10.1016/j.jconrel.2018.12.046.

Date AA, Nagarsenker MS. Single-step and low-energy method to prepare solid lipid nanoparticles and nanostructured lipid carriers using biocompatible solvents. European Journal of Pharmaceutical Research. 2019 March 13;1(1):12-19.

Hoang T, Date AA, Ortiz JO, Young TW, Bensouda S, Xiao P, Marzinke M, Rohan L, Fuchs EJ, Hendrix C, Gumber S, Villinger F, Cone RA, Hanes J, Ensign LM. Development of rectal enema as microbicide (DREAM): Preclinical progressive selection of a tenofovir prodrug enema. European journal of pharmaceutics and biopharmaceutics: official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 2019 May;138:23-29. PubMed PMID: 29802984; PubMed Central PMCID: PMC6428633; DOI: 10.1016/j.ejpb.2018.05.030.

Kulkarni M, Hastak V, Jadhav V, Date AA. Fenugreek Leaf Extract and Its Gel Formulation Show Activity Against Malassezia furfur. Assay and drug development technologies. 2020 January;18(1):45-55. PubMed PMID: 31524496; PubMed Central PMCID: PMC6998042; DOI: 10.1089/adt.2019.918.

Kulkarni M, Goge N, Date AA. Development of Nanoemulsion Preconcentrate of Capsanthin with Improved Chemical Stability. Assay and drug development technologies. 2020 January;18(1):34-44. PubMed PMID: 31502853; PubMed Central PMCID: PMC6998047; DOI: 10.1089/adt.2019.916.

Jacob J, Tan G, Lange I, Saeed H, Date A, Jarvi S. In vitro efficacy of anthelmintics on Angiostrongylus cantonensis L3 larvae. Parasitology. 2021 Feb;148(2):240-250. doi: 10.1017/S0031182020001146. Epub 2020 Aug 17. PubMed PMID: 32799943; NIHMSID:NIHMS1707129.

Kim YC, Shin MD, Hackett SF, Hsueh HT, Lima E Silva R, Date A, Han H, Kim BJ, Xiao A, Kim Y, Ogunnaike L, Anders NM, Hemingway A, He P, Jun AS, McDonnell PJ, Eberhart C, Pitha I, Zack DJ, Campochiaro PA, Hanes J, Ensign LM. Gelling hypotonic polymer solution for extended topical drug delivery to the eye. Nat Biomed Eng. 2020 Nov;4(11):1053-1062. doi: 10.1038/s41551-020-00606-8. Epub 2020 Sep 7. PMID: 32895514; PMCID: PMC7655548.

Yadavalli T, Mallick S, Patel P, Koganti R, Shukla D, Date AA. Pharmaceutically Acceptable Carboxylic Acid-Terminated Polymers Show Activity and Selectivity against HSV-1 and HSV-2 and Synergy with Antiviral Drugs. ACS infectious diseases. 2020 November 13;6(11):2926- 2937. PubMed PMID: 33078609; PubMed Central PMCID: PMC8137138; DOI: 10.1021/acsinfecdis.0c00368.

Kulkarni M, Potdar S, Date AA, Marfatiya A. In Vitro Release Testing of Acyclovir Topical Formulations Using Immersion Cells. Assay and drug development technologies. 2021 February;19(2):75-84. PubMed PMID: 33035072; PubMed Central PMCID: PMC8020522; DOI: 10.1089/adt.2020.995.

Saeed HK, Sutar Y, Patel P, Bhat R, Mallick S, Hatada AE, Koomoa DT, Lange I, Date AA. Synthesis and Characterization of Lipophilic Salts of Metformin to Improve Its Repurposing for Cancer Therapy. ACS omega. 2021 February 2;6(4):2626-2637. PubMed PMID: 33553880; PubMed Central PMCID: PMC7859945; DOI: 10.1021/acsomega.0c04779.

Hsueh HT, Kim YC, Pitha I, Shin MD, Berlinicke CA, Chou RT, Kimball E, Schaub J, Quillen S, Leo KT, Han H, Xiao A, Kim Y, Appell M, Rai U, Kwon H, Kolodziejski P, Ogunnaike L, Anders NM, Hemingway A, Jefferys JL, Date AA, Eberhart C, Johnson TV, Quigley HA, Zack DJ, Hanes J, Ensign LM. Ion-Complex Microcrystal Formulation Provides Sustained Delivery of a Multimodal Kinase Inhibitor from the Subconjunctival Space for Protection of Retinal Ganglion Cells. Pharmaceutics. 2021 May 1;13(5):647. doi: 10.3390/pharmaceutics13050647. PMID: 34062883; PMCID: PMC8147274.

Josyula A, Omiadze R, Parikh K, Kanvinde P, Appell MB, Patel P, Saeed H, Sutar Y, Anders N, He P, McDonnell PJ, Hanes J, Date AA, Ensign LM. An ion-paired moxifloxacin nanosuspension eye drop provides improved prevention and treatment of ocular infection. Bioeng Transl Med. 2021 Jun 22;6(3):e10238. doi: 10.1002/btm2.10238. PMID: 34589607; PMCID: PMC8459599.

Patel P, Pol A, Kalaria D, Date AA, Kalia Y, Patravale V. Microemulsion-based gel for the transdermal delivery of rasagiline mesylate: In vitro and in vivo assessment for Parkinson’s therapy. Eur J Pharm Biopharm. 2021 Aug;165:66-74. doi: 10.1016/j.ejpb.2021.04.026. Epub 2021 May 7. PMID: 33971272.

Golla U, Ehudin MA, Annageldiyev C, Zeng Z, Bastihalli Tukaramrao D, Tarren A, Date AA, Elcheva I, Berg A, Amin S, Loughran TP Jr, Kester M, Desai D, Dovat S, Claxton D, Sharma A. DJ4 Targets the Rho-Associated Protein Kinase Pathway and Attenuates Disease Progression in Preclinical Murine Models of Acute Myeloid Leukemia. Cancers (Basel). 2021 Sep 29;13(19):4889. doi: 10.3390/cancers13194889. PMID: 34638385; PMCID: PMC8508452.

Sutar Y, Fulton SR, Paul S, Altamirano S, Mhatre S, Saeed H, Patel P, Mallick S, Bhat R, Patravale VB, Chauhan H, Nielsen K, Date AA. Docusate-Based Ionic Liquids of Anthelmintic Benzimidazoles Show Improved Pharmaceutical Processability, Lipid Solubility, and in Vitro Activity against Cryptococcus neoformans. ACS Infect Dis. 2021 Sep 10;7(9):2637-2649. doi: 10.1021/acsinfecdis.1c00063. Epub 2021 Sep 1. PMID: 34467755.

Date AA, Kates M, Yoshida T, Babu T, Afzal U, Kanvinde P, Baras A, Anders N, He P, Rudek M, Hanes J, Bivalacqua TJ, Ensign LM. Preclinical evaluation of a hypotonic docetaxel nanosuspension formulation for intravesical treatment of non-muscle-invasive bladder cancer. Drug Deliv Transl Res. 2021 Oct;11(5):2085-2095. doi: 10.1007/s13346-020-00870-w. Epub 2020 Nov 8. PMID: 33164163.

Sutar Y, Yadavalli T, Paul SK, Mallick S, Koganti R, Chauhan H, Date AA, Shukla D. BX795-Organic Acid Coevaporates: Evaluation of Solid-State Characteristics, In Vitro Cytocompatibility and In Vitro Activity against HSV-1 and HSV-2. Pharmaceutics. 2021 Nov 12;13(11):1920. doi: 10.3390/pharmaceutics13111920. PMID: 34834335; PMCID: PMC8623185.

Chen WN, Shaikh MF, Bhuvanendran S, Date A, Ansari MT, Radhakrishnan AK, Othman I. Poloxamer 188 (P188), A Potential Polymeric Protective Agent for Central Nervous System Disorders: A Systematic Review. Curr Neuropharmacol. 2022;20(4):799-808. doi: 10.2174/1570159X19666210528155801. PMID: 34077349.

Liu F, Mallick S, O’Donnell TJ, Rouzimaimaiti R, Luo Y, Sun R, Wall M, Wongwiwatthananukit S, Date A, Silva DK, Williams PG, Chang LC. Coumarinolignans with Reactive Oxygen Species (ROS) and NF-κB Inhibitory Activities from the Roots of Waltheria indica. Molecules. 2022 May 19;27(10):3270. doi: 10.3390/molecules27103270. PMID: 35630746; PMCID: PMC9147481.

Sutar Y, Nabeela S, Singh S, Alqarihi A, Solis N, Ghebremariam T, Filler S, Ibrahim AS, Date A, Uppuluri P. Niclosamide-loaded nanoparticles disrupt Candida biofilms and protect mice from mucosal candidiasis. PLoS Biol. 2022 Aug 17;20(8):e3001762. doi: 10.1371/journal.pbio.3001762. PMID: 35976859; PMCID: PMC9385045.

Nabeela S, Date A, Ibrahim AS, Uppuluri P. Antifungal activity of alexidine dihydrochloride in a novel diabetic mouse model of dermatophytosis. Front Cell Infect Microbiol. 2022 Sep 2;12:958497. doi: 10.3389/fcimb.2022.958497. PMID: 36118019; PMCID: PMC9478942.

Koganti R, Yadavalli T, Sutar Y, Mallick S, Date A, Shukla D. Topical phenylbutyrate antagonizes NF-κB signaling and resolves corneal inflammation. iScience. 2022 Nov 26;25(12):105682. doi: 10.1016/j.isci.2022.105682. PMID: 36536680; PMCID: PMC9758524.

Xiao P, Gumber S, Marzinke MA, Hoang T, Myers R, Date AA, Hanes J, Ensign LM, Wang L, Rohan LC, Cone R, Fuchs EJ, Hendrix CW, Villinger F. Hypo-osmolar rectal douche tenofovir formulation prevents simian/human immunodeficiency virus acquisition in macaques. JCI Insight. 2022 Dec 8;7(23):e161577. doi: 10.1172/jci.insight.161577. PMID: 36477356; PMCID: PMC9746910.

Yadavalli T, Singh SK, Date AA, Shukla D. Tolerability, pharmacokinetics, and anti-herpetic activity of orally administered BX795. Biomed Pharmacother. 2023 Sep;165:115056. doi: 10.1016/j.biopha.2023.115056. Epub 2023 Jul 4. PMID: 37406507.

Sutar Y, Singh SK, Dhoble S, Mali J, Adams J, Yadavalli T, Date AA, Shukla D. Oral Self-Nanoemulsifying System Containing Ionic Liquid of BX795 Is Effective against Genital HSV-2 Infection in Mice. ACS Infect Dis. 2024 Jan 12;10(1):93-106. doi: 10.1021/acsinfecdis.3c00212. Epub 2023 Oct 9. PMID: 37807721.

Pitts MW, Hoffmann PR. Endoplasmic reticulum-resident selenoproteins as regulators of calcium signaling and homeostasis. Cell calcium. 2018 March;70:76-86. PubMed PMID: 28506443; PubMed Central PMCID: PMC5671369.

Gong T, Torres DJ, Berry MJ, Pitts MW. Hypothalamic redox balance and leptin signaling – Emerging role of selenoproteins. Free Radical Biology and Medicine. 2018 March 5. PubMed PMID: 29518483.

Pitts MW. Barnes Maze Procedure for Spatial Learning and Memory in Mice. Bio Protoc. 2018 Mar 5;8(5):e2744. doi: 10.21769/bioprotoc.2744. PMID: 29651452; PMCID: PMC5891830.

Gong T, Hashimoto AC, Sasuclark AR, Khadka VS, Gurary A, Pitts MW. Selenoprotein M Promotes Hypothalamic Leptin Signaling and Thioredoxin Antioxidant Activity. Antioxidants and Redox Signaling. 2019 March 6. PubMed PMID: 30648404; DOI: 10.1089/ars.2018.7594.

Sasuclark AR, Khadka VS, Pitts MW. Cell-Type Specific Analysis of Selenium-Related Genes in Brain. Antioxidants (Basel). 2019 May 5;8(5):120. doi: 10.3390/antiox8050120. PMID: 31060314; PMCID: PMC6562762.

Torres DJ, Pitts MW, Hashimoto AC, Berry MJ. Agrp-Specific Ablation of Scly Protects against Diet-Induced Obesity and Leptin Resistance. Nutrients. 2019 Jul 23;11(7):1693. doi: 10.3390/nu11071693. PMID: 31340540; PMCID: PMC6682868.

Kilonzo VW, Sweet RA, Glausier JR, Pitts MW. Deficits in Glutamic Acid Decarboxylase 67 Immunoreactivity, Parvalbumin Interneurons, and Perineuronal Nets in the Inferior Colliculus of Subjects With Schizophrenia. Schizophr Bull. 2020 Jul 18;46(5):1053–9. doi: 10.1093/schbul/sbaa082. Epub ahead of print. PMID: 32681171; PMCID: PMC7505180.

Seale LA, Torres DJ, Berry MJ, Pitts MW. A role for selenium-dependent GPX1 in SARS-CoV-2 virulence. Am J Clin Nutr. 2020 Aug 1;112(2):447-448. doi: 10.1093/ajcn/nqaa177. PMID: 32592394; PMCID: PMC7337667.

Fujimoto BA, Young M, Nakamura N, Ha H, Carter L, Pitts MW, Torres D, Noh HL, Suk S, Kim JK, Polgar N. Disrupted glucose homeostasis and skeletal muscle-specific glucose uptake in an exocyst knockout mouse model. The Journal of biological chemistry. 2021 February 26:100482. PubMed PMID: 33647317; PubMed Central PMCID: PMC8027262; DOI: 10.1016/j.jbc.2021.100482.

Kilonzo VW, Sasuclark AR, Torres DJ, Coyle C, Pilat JM, Williams CS, Pitts MW. Juvenile Selenium Deficiency Impairs Cognition, Sensorimotor Gating, and Energy Homeostasis in Mice. Front Nutr. 2021 May 7;8:667587. doi: 10.3389/fnut.2021.667587. PMID: 34026810; PMCID: PMC8138326.

Torres DJ, Pitts MW. Pericytic porters: helping leptin step in. Trends Endocrinol Metab. 2021 Aug 19:S1043-2760(21)00181-8. doi: 10.1016/j.tem.2021.08.001. Epub ahead of print. PMID: 34420855.

Torres DJ, Pitts MW, Seale LA, Hashimoto AC, An KJ, Hanato AN, Hui KW, Remigio SMA, Carlson BA, Hatfield DL, Berry MJ. Female Mice with Selenocysteine tRNA Deletion in Agrp Neurons Maintain Leptin Sensitivity and Resist Weight Gain While on a High-Fat Diet. Int J Mol Sci. 2021 Oct 12;22(20):11010. doi: 10.3390/ijms222011010. PMID: 34681674; PMCID: PMC8539086.

Pitts MW, Hoffmann PR, Schomburg L. Editorial: Selenium and Selenoproteins in Brain Development, Function, and Disease. Front Neurosci. 2022 Jan 13;15:821140. doi: 10.3389/fnins.2021.821140. PMID: 35095409; PMCID: PMC8792733.

Nunes LGA, Pitts MW, Hoffmann PR. Selenoprotein I (selenoi) as a critical enzyme in the central nervous system. Arch Biochem Biophys. 2022 Aug 22:109376. doi: 10.1016/j.abb.2022.109376. Epub ahead of print. PMID: 36007576.

Ma C, Hoffmann FW, Nunes LG, Urena F, Andrukhiv A, Gerschenson M, Pitts MW, Hoffmann PR. Selenoprotein I deficiency in T cells promotes differentiation into tolerant phenotypes while decreasing Th17 pathology. J Leukoc Biol. 2022 Dec;112(6):1387-1397. doi: 10.1002/JLB.1A0122-080R. Epub 2022 Aug 2. PMID: 35916034; PMCID: PMC9701159.

An KJ, Hanato AN, Hui KW, Pitts MW, Seale LA, Nicholson JL, Toh P, Kim JK, Berry MJ, Torres DJ. Selenium Protects Mouse Hypothalamic Cells from Glucocorticoid-Induced Endoplasmic Reticulum Stress Vulnerability and Insulin Signaling Impairment. Antioxidants (Basel). 2023 Feb 20;12(2):526. doi: 10.3390/antiox12020526. PMID: 36830084; PMCID: PMC9952756.

Nunes LGA, Ma C, Hoffmann FW, Shay AE, Pitts MW, Hoffmann PR. Selenoprotein I is indispensable for ether lipid homeostasis and proper myelination. J Biol Chem. 2024 Apr 4;300(5):107259. doi: 10.1016/j.jbc.2024.107259. Epub ahead of print. PMID: 38582453; PMCID: PMC11061234.

Cheung EC, Kay MW, Schunke KJ. Epigenetic Alterations in Pediatric Sleep Apnea. Int J Mol Sci. 2021 Sep 1;22(17):9523. doi: 10.3390/ijms22179523. PMID: 34502428; PMCID: PMC8430725.

Rodriguez J, Escobar JB, Cheung EC, Kowalik G, Russo R, Dyavanapalli J, Alber BR, Harral G, Gill A, Melkie M, Jain V, Schunke KJ, Mendelowitz D, Kay MW. Hypothalamic Oxytocin Neuron Activation Attenuates Intermittent Hypoxia-Induced Hypertension and Cardiac Dysfunction in an Animal Model of Sleep Apnea. Hypertension. 2023 Apr;80(4):882-894. doi: 10.1161/HYPERTENSIONAHA.122.20149. Epub 2023 Feb 16. PMID: 36794581; PMCID: PMC10027399.

Schunke KJ, Rodriguez J, Dyavanapalli J, Schloen J, Wang X, Escobar J, Kowalik G, Cheung EC, Ribeiro C, Russo R, Alber BR, Dergacheva O, Chen SW, Murillo-Berlioz AE, Lee KB, Trachiotis G, Entcheva E, Brantner CA, Mendelowitz D, Kay MW. Outcomes of hypothalamic oxytocin neuron-driven cardioprotection after acute myocardial infarction. Basic Res Cardiol. 2023 Oct 6;118(1):43. doi: 10.1007/s00395-023-01013-1. PMID: 37801130; PMCID: PMC10558415.

Schunke KJ, Kay MW, Mendelowitz D. Chapter 9 – Neuroendocrinology Therapeutic Pathways for Cardiovascular Disease. Book chapter in: Yosten G, Cunningham DW, editors. Cardiovascular Neuroendocrinology. In press.

Green CD, Ma Q, Manske GL, Shami AN, Zheng X, Marini S, Moritz L, Sultan C, Gurczynski SJ, Moore BB, Tallquist MD, Li JZ, Hammoud SS. A Comprehensive Roadmap of Murine Spermatogenesis Defined by Single-Cell RNA-Seq. Developmental cell. 2018 September 10;46(5):651-667.e10. PubMed PMID: 30146481; DOI: 10.1016/j.devcel.2018.07.025.

Park J, Ivey MJ, Deana Y, Riggsbee KL, Sörensen E, Schwabl V, Sjöberg C, Hjertberg T, Park GY, Swonger JM, Rosengreen T, Morty RE, Ahlbrecht K, Tallquist MD. The Tcf21 lineage constitutes the lung lipofibroblast population. American journal of physiology. Lung cellular and molecular physiology. 2019 May 1;316(5):L872-L885. PubMed PMID: 30675802; DOI: 10.1152/ajplung.00254.2018.

Wirka RC, Wagh D, Paik DT, Pjanic M, Nguyen T, Miller CL, Kundu R, Nagao M, Coller J, Koyano TK, Fong R, Woo YJ, Liu B, Montgomery SB, Wu JC, Zhu K, Chang R, Alamprese M, Tallquist MD, Kim JB, Quertermous T. Atheroprotective roles of smooth muscle cell phenotypic modulation and the TCF21 disease gene as revealed by single-cell analysis. Nat Med. 2019 Aug;25(8):1280-1289. doi: 10.1038/s41591-019-0512-5. Epub 2019 Jul 29. PMID: 31359001; PMCID: PMC7274198.
Ivey MJ, Kuwabara JT, Riggsbee KL, Tallquist MD. Platelet-derived growth factor receptor-α is essential for cardiac fibroblast survival. Am J Physiol Heart Circ Physiol. 2019 Aug 1;317(2):H330-H344. doi: 10.1152/ajpheart.00054.2019. Epub 2019 May 24. PMID: 31125253; PMCID: PMC6732481.

Tallquist MD. Cardiac Fibroblast Diversity. Annu Rev Physiol. 2020 Feb 10;82:63-78. doi: 10.1146/annurev-physiol-021119-034527. PMID: 32040933.

Tallquist MD. Developmental Pathways of Cardiac Fibroblasts. Cold Spring Harb Perspect Biol. 2020 Apr 1;12(4):a037184. doi: 10.1101/cshperspect.a037184. PMID: 31570334; PMCID: PMC7111248.

Shen YC, Shami AN, Moritz L, Larose H, Manske GL, Ma Q, Zheng X, Sukhwani M, Czerwinski M, Sultan C, Chen H, Gurczynski SJ, Spence JR, Orwig KE, Tallquist M, Li JZ, Hammoud SS. TCF21+ mesenchymal cells contribute to testis somatic cell development, homeostasis, and regeneration in mice. Nat Commun. 2021 Jun 23;12(1):3876. doi: 10.1038/s41467-021-24130-8. PMID: 34162856; PMCID: PMC8222243.

Francisco J, Zhang Y, Jeong JI, Mizushima W, Ikeda S, Ivessa A, Oka S, Zhai P, Tallquist MD, Del Re DP. Blockade of Fibroblast YAP Attenuates Cardiac Fibrosis and Dysfunction Through MRTF-A Inhibition. JACC Basic Transl Sci. 2020 Sep 28;5(9):931-945. doi: 10.1016/j.jacbts.2020.07.009. Erratum in: JACC Basic Transl Sci. 2021 Jul 26;6(7):629. PMID: 33015415; PMCID: PMC7524792.

Kuwabara JT, Hara A, Heckl JR, Peña B, Bhutada S, DeMaris R, Ivey MJ, DeAngelo LP, Liu X, Park J, Jahansooz JR, Mestroni L, McKinsey TA, Apte SS, Tallquist MD. Regulation of extracellular matrix composition by fibroblasts during perinatal cardiac maturation. J Mol Cell Cardiol. 2022 May 13;169:84-95. doi: 10.1016/j.yjmcc.2022.05.003. Epub ahead of print. PMID: 35569524.

Umbarkar P, Tousif S, Singh AP, Anderson JC, Zhang Q, Tallquist MD, Woodgett J, Lal H. Fibroblast GSK-3α Promotes Fibrosis via RAF-MEK-ERK Pathway in the Injured Heart. Circ Res. 2022 Sep 16;131(7):620-636. doi: 10.1161/CIRCRESAHA.122.321431. Epub 2022 Sep 2. PMID: 36052698; PMCID: PMC9481711.

Giannakopoulos S, Strange DP, Jiyarom B, Abdelaal O, Bradshaw AW, Nerurkar VR, Ward MA, Bakse J, Yap J, Vanapruks S, Boisvert W, Tallquist MD, Shikuma C, Sadri-Ardekani H, Clapp P, Murphy S, Verma S. In vitro evidence against productive SARS-CoV-2 infection of human testicular cells: Bystander effects of infection mediate testicular injury. bioRxiv [Preprint]. 2022 Sep 22:2022.09.21.508904. doi: 10.1101/2022.09.21.508904. PMID: 36172118; PMCID: PMC9516847.

Kuwabara JT, Hara A, Bhutada S, Gojanovich GS, Chen J, Hokutan K, Shettigar V, Lee AY, DeAngelo LP, Heckl JR, Jahansooz JR, Tacdol DK, Ziolo MT, Apte SS, Tallquist MD. Consequences of PDGFRα+ fibroblast reduction in adult murine hearts. Elife. 2022 Sep 23;11:e69854. doi: 10.7554/eLife.69854. PMID: 36149056; PMCID: PMC9576271.

Dean LS, Devendra G, Jiyarom B, Subia N, Tallquist MD, Nerurkar VR, Chang SP, Chow DC, Shikuma CM, Park J. Phenotypic alteration of low-density granulocytes in people with pulmonary post-acute sequalae of SARS-CoV-2 infection. Front Immunol. 2022 Dec 15;13:1076724. doi: 10.3389/fimmu.2022.1076724. PMID: 36591237; PMCID: PMC9797994.

Hara A, Tallquist MD. Fibroblast and Immune Cell Cross-Talk in Cardiac Fibrosis. Curr Cardiol Rep. 2023 Jun;25(6):485-493. doi: 10.1007/s11886-023-01877-8. Epub 2023 Apr 19. PMID: 37074566.

Dean LS, Devendra G, Jiyarom B, Subia N, Tallquist MD, Nerurkar VR, Chang SP, Chow DC, Shikuma CM, Park J. Corrigendum: Phenotypic alteration of low-density granulocytes in people with pulmonary post-acute sequelae of SARS-CoV-2 infection. Front Immunol. 2023 Apr 28;14:1209624. doi: 10.3389/fimmu.2023.1209624. Erratum for: Front Immunol. 2022 Dec 15;13:1076724. PMID: 37187732; PMCID: PMC10176967.

Giannakopoulos S, Strange DP, Jiyarom B, Abdelaal O, Bradshaw AW, Nerurkar VR, Ward MA, Bakse J, Yap J, Vanapruks S, Boisvert WA, Tallquist MD, Shikuma C, Sadri-Ardekani H, Clapp P, Murphy SV, Verma S. In vitro evidence against productive SARS-CoV-2 infection of human testicular cells: Bystander effects of infection mediate testicular injury. PLoS Pathog. 2023 May 18;19(5):e1011409. doi: 10.1371/journal.ppat.1011409. PMID: 37200377; PMCID: PMC10231791.

Park J, Dean LS, Heckl J, Gangcuangco LM, Pedro TK, Tallquist MD, Seto TB, Shiramizu B, Chow DC, Shikuma CM. Low-density granulocytes display immature cells with enhanced NET formation in people living with HIV. Sci Rep. 2023 Aug 16;13(1):13282. doi: 10.1038/s41598-023-40475-0. PMID: 37587169; PMCID: PMC10432506.

Mayr CH, Sengupta A, Asgharpour S, Ansari M, Pestoni JC, Ogar P, Angelidis I, Liontos A, Rodriguez-Castillo JA, Lang NJ, Strunz M, Porras-Gonzalez D, Gerckens M, De Sadeleer LJ, Oehrle B, Viteri-Alvarez V, Fernandez IE, Tallquist M, Irmler M, Beckers J, Eickelberg O, Stoleriu GM, Behr J, Kneidinger N, Wuyts WA, Wasnick RM, Yildirim AÖ, Ahlbrecht K, Morty RE, Samakovlis C, Theis FJ, Burgstaller G, Schiller HB. Sfrp1 inhibits lung fibroblast invasion during transition to injury-induced myofibroblasts. Eur Respir J. 2024 Feb 8;63(2):2301326. doi: 10.1183/13993003.01326-2023. PMID: 38212077; PMCID: PMC10850614.

Nguyen TB, Lac Q, Abdi L, Banerjee D, Deng Y, Zhang Y. Harshening stem cell research and precision medicine: The states of human pluripotent cells stem cell repository diversity, and racial and sex differences in transcriptomes. Front Cell Dev Biol. 2023 Jan 4;10:1071243. doi: 10.3389/fcell.2022.1071243. PMID: 36684445; PMCID: PMC9848738.

Zhang Z, Freeman M, Zhang Y, El-Nachef D, Davenport G, Williams A, MacLellan WR. Hippo signaling and histone methylation control cardiomyocyte cell cycle re-entry through distinct transcriptional pathways. PLoS One. 2023 Feb 13;18(2):e0281610. doi: 10.1371/journal.pone.0281610. PMID: 36780463; PMCID: PMC9925018.